Vps16 - VSP16 CORVET/HOPS core subunit Gene

Also Known as mVPS16; 1810074M16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 80743

Summary

Enables actin binding activity. Acts upstream of or within viral entry into host cell. Located in actin filament; clathrin-coated vesicle; and early endosome membrane. Part of AP-3 adaptor complex and CORVET complex. Human ortholog(s) of this gene implicated in dystonia. Orthologous to human VPS16 (VPS16 core subunit of CORVET and HOPS complexes). [provided by Alliance of Genome Resources, Apr 2022]

Vps16 Products (2)

mRNA Protein Name
NM_001362651.1 NP_001349580.1 vacuolar protein sorting-associated protein 16 homolog isoform 2
NM_030559.3 NP_085036.3 vacuolar protein sorting-associated protein 16 homolog isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin binding IDA
IDA: Inferred from direct assay
14668490 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
14668490 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within symbiont entry into host cell IMP
IMP: Inferred from mutant phenotype
24550300 MGI
Cellular Component GO Annotation Evidence References Source
part of AP-3 adaptor complex IDA
IDA: Inferred from direct assay
21411634 MGI
part of CORVET complex IDA
IDA: Inferred from direct assay
25266290 MGI
located in actin filament IDA
IDA: Inferred from direct assay
14668490 MGI
located in clathrin-coated vesicle IDA
IDA: Inferred from direct assay
21411634 MGI
located in early endosome IDA
IDA: Inferred from direct assay
14668490 MGI
located in early endosome membrane IDA
IDA: Inferred from direct assay
21411634 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vacuolar protein sorting-associated protein 16 homolog

  • vacuolar protein sorting 16

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15676 VPS16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vps16 NCBI NCBI:64601