H1f1 - H1.1 linker histone, cluster member Gene

Also Known as H1a; H1-1; H1.1; H1var3; Hist1h1a

Species: Mus musculus

Gene Type: protein coding
Gene ID: 80838

Summary

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. [provided by RefSeq, Aug 2015]

H1f1 Products (2)

mRNA Protein Name
NM_030609.3 NP_085112.1 histone H1.1
NM_030609.3 NP_085112.1 histone H1.1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
15562002 MGI
enables heparin binding IDA
IDA: Inferred from direct assay
9664069 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9664069 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of receptor-mediated endocytosis IDA
IDA: Inferred from direct assay
9664069 MGI
acts upstream of or within spermatogenesis IGI
IGI: Inferred from genetic interaction
15051954 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
9664069 MGI
located in nucleus IDA
IDA: Inferred from direct assay
9664069 MGI
located in vesicle IDA
IDA: Inferred from direct assay
9664069 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histone H1.1

  • H1 VAR.3

  • H1 histone family, member 1

  • histone 1, H1a

  • histone H1a

  • histone cluster 1, H1a

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05945 H1-1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown