Lrba - LPS-responsive beige-like anchor Gene

Also Known as Lba; Lab300; D3Ertd775e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 80877

Summary

Predicted to enable protein kinase A binding activity and protein kinase binding activity. Acts upstream of or within cellular response to Leukemia Inhibitory Factor. Located in several cellular components, including endoplasmic reticulum; lysosome; and trans-Golgi network. Is expressed in branchial arch; central nervous system; limb; sensory organ; and somite. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human LRBA (LPS responsive beige-like anchor protein). [provided by Alliance of Genome Resources, Apr 2022]

Lrba Products (3)

mRNA Protein Name
NM_001077687.1 NP_001071155.1 lipopolysaccharide-responsive and beige-like anchor protein isoform gamma
NM_001077688.1 NP_001071156.1 lipopolysaccharide-responsive and beige-like anchor protein isoform beta
NM_030695.2 NP_109620.2 lipopolysaccharide-responsive and beige-like anchor protein isoform alpha

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
11254716 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
11254716 MGI
located in lysosome IDA
IDA: Inferred from direct assay
11254716 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
11254716 MGI
located in trans-Golgi network IDA
IDA: Inferred from direct assay
11254716 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lipopolysaccharide-responsive and beige-like anchor protein

  • beige-like protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07777 LRBA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22224 Lrba Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28746 Lrba Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lrba NCBI NCBI:987