Pum1 - pumilio RNA-binding family member 1 Gene

Also Known as Pumm; mKIAA0099

Species: Mus musculus

Gene Type: protein coding
Gene ID: 80912

Summary

Enables mRNA 3'-UTR binding activity. Involved in several processes, including adult locomotory behavior; posttranscriptional regulation of gene expression; and spermatogenesis. Acts upstream of or within posttranscriptional regulation of gene expression. Located in cytoplasm. Is expressed in several structures, including central nervous system; intestine; olfactory epithelium; retina; and testis. Human ortholog(s) of this gene implicated in cerebellar ataxia type 47. Orthologous to human PUM1 (pumilio RNA binding family member 1). [provided by Alliance of Genome Resources, Apr 2022]

Pum1 Products (8)

mRNA Protein Name
NM_001159603.2 NP_001153075.1 pumilio homolog 1 isoform 2
NM_001159604.2 NP_001153076.1 pumilio homolog 1 isoform 3
NM_001159605.2 NP_001153077.1 pumilio homolog 1 isoform 4
NM_001159606.2 NP_001153078.1 pumilio homolog 1 isoform 5
NM_001356564.1 NP_001343493.1 pumilio homolog 1 isoform 6
NM_001356565.1 NP_001343494.1 pumilio homolog 1 isoform 7
NM_001356566.1 NP_001343495.1 pumilio homolog 1 isoform 8
NM_030722.3 NP_109647.2 pumilio homolog 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables mRNA 3'-UTR binding IDA
IDA: Inferred from direct assay
22342750 MGI
Biological Process GO Annotation Evidence References Source
involved in adult locomotory behavior IMP
IMP: Inferred from mutant phenotype
25768905 MGI
involved in mRNA destabilization IDA
IDA: Inferred from direct assay
25768905 MGI
involved in post-transcriptional gene silencing IMP
IMP: Inferred from mutant phenotype
22342750 MGI
acts upstream of or within post-transcriptional regulation of gene expression IMP
IMP: Inferred from mutant phenotype
25100735 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
22342750 MGI
involved in stem cell differentiation IMP
IMP: Inferred from mutant phenotype
24412312 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
22342750 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pumilio homolog 1

  • pumilio 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11461 PUM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pum1 NCBI NCBI:9698