Itga7 - integrin subunit alpha 7 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81008

Summary

Enables Integrin binding activity and laminin binding activity. Involved in cell adhesion; integrin-mediated signaling pathway; and skeletal muscle tissue development. Located in cell surface. Part of Integrin complex. Used to study cardiomyopathy. Biomarker of arteriosclerosis. Human ortholog(s) of this gene implicated in Duchenne muscular dystrophy; congenital muscular dystrophy due to Integrin alpha-7 deficiency; and muscular disease. Orthologous to human ITGA7 (Integrin subunit alpha 7). [provided by Alliance of Genome Resources, Apr 2022]

Itga7 Products (1)

mRNA Protein Name
NM_030842.1 NP_110469.1 integrin alpha-7 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cell adhesion molecule binding IDA
IDA: Inferred from direct assay
1315319 RGD
enables integrin binding IPI
IPI: Inferred from physical interaction
1315319 RGD
enables laminin binding IDA
IDA: Inferred from direct assay
1315319 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
20019333 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
1315319 RGD
Biological Process GO Annotation Evidence References Source
involved in cell adhesion IDA
IDA: Inferred from direct assay
1315319 RGD
involved in cell adhesion IMP
IMP: Inferred from mutant phenotype
16282198 RGD
involved in integrin-mediated signaling pathway IDA
IDA: Inferred from direct assay
1315319 RGD
involved in skeletal muscle tissue development IEP
IEP: Inferred from expression pattern
1315319 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
1315319 RGD
part of integrin complex IDA
IDA: Inferred from direct assay
1315319 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

integrin alpha-7

  • H36-alpha7

  • alpha 7A integrin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06954 ITGA7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20969 Itga7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27486 Itga7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Itga7 NCBI NCBI:3679