Stxbp5 - syntaxin binding protein 5 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81022

Summary

Enables syntaxin-1 binding activity. Involved in synaptic vesicle cycle. Is active in several cellular components, including Schaffer collateral - CA1 synapse; presynaptic cytosol; and synaptic vesicle. Is extrinsic component of presynaptic membrane. Orthologous to human STXBP5 (syntaxin binding protein 5). [provided by Alliance of Genome Resources, Apr 2022]

Stxbp5 Products (3)

mRNA Protein Name
NM_030843.3 NP_110470.1 syntaxin-binding protein 5 isoform m
NM_178345.2 NP_848035.1 syntaxin-binding protein 5 isoform b
NM_178346.2 NP_848036.1 syntaxin-binding protein 5 isoform s

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables syntaxin-1 binding IDA
IDA: Inferred from direct assay
9620695 RGD
Biological Process GO Annotation Evidence References Source
involved in synaptic vesicle cycle IDA
IDA: Inferred from direct assay
27807164 RGD
involved in synaptic vesicle cycle IMP
IMP: Inferred from mutant phenotype
27807164 RGD
Cellular Component GO Annotation Evidence References Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
9620695 RGD
is active in extrinsic component of presynaptic membrane IDA
IDA: Inferred from direct assay
9620695 RGD
is active in neuromuscular junction IDA
IDA: Inferred from direct assay
9620695 RGD
is active in presynapse IDA
IDA: Inferred from direct assay
16186257 RGD
is active in presynaptic cytosol IDA
IDA: Inferred from direct assay
9620695 RGD
is active in synaptic vesicle EXP
EXP: Inferred from Experiment
17110340 RGD
is active in synaptic vesicle IDA
IDA: Inferred from direct assay
17110340 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

syntaxin-binding protein 5

  • lethal(2) giant larvae protein homolog 3

  • tomosyn

  • tomosyn-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13993 STXBP5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13994 STXBP5L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Stxbp5 NCBI NCBI:134957