ACSBG2 - acyl-CoA synthetase bubblegum family member 2 Gene

Also Known as BGR; BRGL; PRTDNY3; PRTD-NY3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 81616

About ACSBG2

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:6,135,633-6,193,091 (from NCBI)

This gene has 15 transcripts (splice variants), 263 orthologues and 12 paralogues. Restricted expression toward testis (RPKM 79.4).

Summary

Enables acyl-CoA hydrolase activity and arachidonate-CoA Ligase activity. Acts upstream of or within fatty acid metabolic process. Located in cytosol and mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

ACSBG2 Products (6)

mRNA Protein Name
NM_001289177.2 NP_001276106.1 long-chain-fatty-acid--CoA ligase ACSBG2 isoform a
NM_001289178.2 NP_001276107.1 long-chain-fatty-acid--CoA ligase ACSBG2 isoform a
NM_001289179.2 NP_001276108.1 long-chain-fatty-acid--CoA ligase ACSBG2 isoform b
NM_001289180.2 NP_001276109.1 long-chain-fatty-acid--CoA ligase ACSBG2 isoform c
NM_001321384.2 NP_001308313.1 long-chain-fatty-acid--CoA ligase ACSBG2 isoform d
NM_030924.5 NP_112186.3 long-chain-fatty-acid--CoA ligase ACSBG2 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables arachidonate-CoA ligase activity IDA
IDA: Inferred from direct assay
16762313 GOA
enables fatty acyl-CoA hydrolase activity IDA
IDA: Inferred from direct assay
16762313 GOA
enables long-chain fatty acid-CoA ligase activity IDA
IDA: Inferred from direct assay
16371355 GOA
Biological Process GO Annotation Evidence References Source
acts upstream of or within fatty acid metabolic process IDA
IDA: Inferred from direct assay
16371355 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
16371355 GOA
located in mitochondrion IDA
IDA: Inferred from direct assay
16762313 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ACSBG2 Protein Structure

AMP-binding

AMP-binding: AMP-binding enzyme (57 - 518)

  • 0
  • 200
  • 400
  • 600
  • 666 a.a.
Protein Preferred Names Protein Names

long-chain-fatty-acid--CoA ligase ACSBG2

  • arachidonate--CoA ligase ACSBG2

Related Diseases

Diseases Alias
Ceroid Lipofuscinosis, Neuronal, 1

  • Neuronal Ceroid Lipofuscinosis 1

  • CLN1

  • Infantile Neuronal Ceroid Lipofuscinosis

  • Cln1 Disease

  • Santavuori-Haltia Disease

  • Ceroid Lipofuscinosis, Neuronal, 1, Variable Age At Onset

  • Neuronal Ceroid Lipofuscinosis 1 Variable Age Of Onset

  • Ceroid Lipofuscinosis Neuronal 1

  • Cln1 Variable Age At Onset

  • Infantile Batten Disease

  • Neuronal Ceroid Lipofuscinosis, Infantile

  • Hagberg-Santavuori Disease

  • Incl

  • Juvenile Neuronal Ceroid Lipofuscinosis With Granular Osmiophilic Deposits

  • Neuronal Ceroid Lipofuscinosis With Variable Age At Onset

  • Santavuori Disease

  • Lipofuscinosis, Ceroid, Neuronal, Type 1

  • Ceroid Lipofuscinosis, Neuronal 1, Infantile
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00197 ACSBG2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ACSBG2 VGNC VGNC:54569
Mus musculus ACSBG2 MGD MGI:3587728
Macaca mulatta ACSBG2 VGNC VGNC:69525
Rattus norvegicus ACSBG2 RGD RGD:1588580
Bos taurus ACSBG2 VGNC VGNC:25561
Others ACSBG2 NCBI