2. Gene
  3. Gna11 - G protein subunit alpha 11 Gene

Gna11 - G protein subunit alpha 11 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Hg1k

Gene ID: 81662 | Gene type: protein coding

About Gna11

Summary

Enables alkylglycerophosphoethanolamine phosphodiesterase activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; cranial skeletal system development; and multicellular organism aging. Predicted to act upstream of or within several processes, including cellular response to pH; regulation of melanocyte differentiation; and skeletal system development. Located in cytosol and plasma membrane. Part of heterotrimeric G-protein complex. Human ortholog(s) of this gene implicated in autosomal dominant hypocalcemia 2 and familial hypocalciuric hypercalcemia 2. Orthologous to human GNA11 (G protein subunit alpha 11). [provided by Alliance of Genome Resources, Apr 2022]

Gna11 Products(1)

mRNA Protein Name
NM_031033.2 NP_112295.2 guanine nucleotide-binding protein subunit alpha-11
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables alkylglycerophosphoethanolamine phosphodiesterase activity IDA
IDA: Inferred from direct assay
21812758 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
20548297 RGD
Cellular Component GO Annotation Evidence Reference Source
part of heterotrimeric G-protein complex IDA
IDA: Inferred from direct assay
21812758 RGD
is active in presynapse IDA
IDA: Inferred from direct assay
17144906 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanine nucleotide-binding protein subunit alpha-11

g alpha-11

guanine nucleotide binding protein, alpha 11

guanine nucleotide regulatory protein G alpha 11

guanine nucleotide-binding protein alpha 11 subunit

heterotrimeric guanine nucleotide-binding protein 1k

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05529 GNA11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gna11 NCBI NCBI:2767