Gna11 - G protein subunit alpha 11 Gene

Also Known as Hg1k

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81662

Summary

Enables alkylglycerophosphoethanolamine phosphodiesterase activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; cranial skeletal system development; and multicellular organism aging. Predicted to act upstream of or within several processes, including cellular response to pH; regulation of melanocyte differentiation; and skeletal system development. Located in cytosol and plasma membrane. Part of heterotrimeric G-protein complex. Human ortholog(s) of this gene implicated in autosomal dominant hypocalcemia 2 and familial hypocalciuric hypercalcemia 2. Orthologous to human GNA11 (G protein subunit alpha 11). [provided by Alliance of Genome Resources, Apr 2022]

Gna11 Products (1)

mRNA Protein Name
NM_031033.2 NP_112295.2 guanine nucleotide-binding protein subunit alpha-11

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables alkylglycerophosphoethanolamine phosphodiesterase activity IDA
IDA: Inferred from direct assay
21812758 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
20548297 RGD
Cellular Component GO Annotation Evidence References Source
part of heterotrimeric G-protein complex IDA
IDA: Inferred from direct assay
21812758 RGD
is active in presynapse IDA
IDA: Inferred from direct assay
17144906 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanine nucleotide-binding protein subunit alpha-11

  • g alpha-11

  • guanine nucleotide binding protein, alpha 11

  • guanine nucleotide regulatory protein G alpha 11

  • guanine nucleotide-binding protein alpha 11 subunit

  • heterotrimeric guanine nucleotide-binding protein 1k

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05529 GNA11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gna11 NCBI NCBI:2767