Gna12 - G protein subunit alpha 12 Gene

Also Known as Hg1m1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81663

Summary

Enables D5 Dopamine Receptor binding activity. Involved in response to xenobiotic stimulus. Acts upstream of or within G protein-coupled receptor signaling pathway; negative regulation of vascular associated smooth muscle cell migration; and negative regulation of vascular associated smooth muscle cell proliferation. Located in brush border membrane. Orthologous to human GNA12 (G protein subunit alpha 12). [provided by Alliance of Genome Resources, Apr 2022]

Gna12 Products (1)

mRNA Protein Name
NM_031034.2 NP_112296.1 guanine nucleotide-binding protein subunit alpha-12

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables D5 dopamine receptor binding IPI
IPI: Inferred from physical interaction
12623966 RGD
Biological Process GO Annotation Evidence References Source
acts upstream of or within G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
29453251 RGD
acts upstream of or within negative regulation of vascular associated smooth muscle cell migration IMP
IMP: Inferred from mutant phenotype
29453251 RGD
acts upstream of or within negative regulation of vascular associated smooth muscle cell proliferation IMP
IMP: Inferred from mutant phenotype
29453251 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
12623966 RGD
Cellular Component GO Annotation Evidence References Source
located in brush border membrane IDA
IDA: Inferred from direct assay
12623966 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanine nucleotide-binding protein subunit alpha-12

  • g alpha-12

  • guanine nucleotide binding protein (G protein) alpha 12

  • guanine nucleotide binding protein, alpha 12

  • heterotrimeric guanine nucleotide-binding protein 1m1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05530 GNA12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gna12 NCBI NCBI:2768