Chrna6 - cholinergic receptor nicotinic alpha 6 subunit Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81721

Summary

Contributes to heterocyclic compound binding activity. Predicted to be involved in several processes, including chemical synaptic transmission; regulation of membrane potential; and regulation of synaptic vesicle exocytosis. Predicted to act upstream of or within membrane depolarization and regulation of dopamine secretion. Located in membrane. Part of protein-containing complex. Is integral component of postsynaptic membrane and integral component of presynaptic membrane. Orthologous to human CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit). [provided by Alliance of Genome Resources, Apr 2022]

Chrna6 Products (1)

mRNA Protein Name
NM_057184.2 NP_476532.2 neuronal acetylcholine receptor subunit alpha-6 precursor
Molecular Function GO Annotation Evidence References Source
contributes to heterocyclic compound binding IDA
IDA: Inferred from direct assay
22550286 RGD
Cellular Component GO Annotation Evidence References Source
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
24607281 RGD
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
24607281 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
16129735 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuronal acetylcholine receptor subunit alpha-6

  • cholinergic receptor, nicotinic, alpha 6 (neuronal)

  • cholinergic receptor, nicotinic, alpha polypeptide 6

Orthologs Information

Species Symbol Source ID
Homo sapiens Chrna6 NCBI NCBI:8973