Hip1r - huntingtin interacting protein 1 related Gene

Rattus norvegicus

Gene ID: 81917 | Gene type: protein coding

About Hip1r

Summary

Predicted to enable several functions, including clathrin binding activity; phosphatidylinositol phosphate binding activity; and protein dimerization activity. Predicted to be involved in several processes, including positive regulation of signal transduction; regulation of apoptotic process; and regulation of organelle organization. Predicted to act upstream of or within receptor-mediated endocytosis. Located in membrane. Orthologous to human HIP1R (Huntingtin interacting protein 1 related). [provided by Alliance of Genome Resources, Apr 2022]

Hip1r Products(2)

mRNA	Protein	Name
NM_001134763.1	NP_001128235.1	huntingtin-interacting protein 1-related protein isoform 1
NM_031234.1	NP_112513.1	huntingtin-interacting protein 1-related protein isoform 2

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
involved in postsynapse organization	IDA IDA: Inferred from direct assay	28663723	RGD
involved in postsynapse organization	IMP IMP: Inferred from mutant phenotype	28663723	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	12650982	RGD
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	28663723	RGD
is active in postsynapse	IDA IDA: Inferred from direct assay	12650982	RGD
is active in postsynaptic endocytic zone	IDA IDA: Inferred from direct assay	35072626	RGD
is active in postsynaptic endocytic zone	IMP IMP: Inferred from mutant phenotype	35072626	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

huntingtin-interacting protein 1-related protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-179558	MS1-96	Degrader	/	Unkown
HY-RS06180	HIP1R Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Hip1r	NCBI	NCBI:9026

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