2. Gene
  3. Akap12 - A kinase (PRKA) anchor protein (gravin) 12 Gene

Akap12 - A kinase (PRKA) anchor protein (gravin) 12 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Srcs5; SSeCKS; Tsga12

Gene ID: 83397 | Gene type: protein coding

About Akap12

Summary

Predicted to enable Adenylate Cyclase binding activity. Involved in modulation of chemical synaptic transmission. Is active in Schaffer collateral - CA1 synapse. Is expressed in central nervous system; gut; neural ectoderm; renal interstitium; and retina. Human ortholog(s) of this gene implicated in chronic kidney disease; colorectal carcinoma; and juvenile myelomonocytic leukemia. Orthologous to human AKAP12 (A-kinase anchoring protein 12). [provided by Alliance of Genome Resources, Apr 2022]

Akap12 Products(1)

mRNA Protein Name
NM_031185.3 NP_112462.1 A-kinase anchor protein 12
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
23238728 MGI
involved in modulation of chemical synaptic transmission IEP
IEP: Inferred from expression pattern
23238728 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
23238728 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
23238728 MGI
is active in Schaffer collateral - CA1 synapse IEP
IEP: Inferred from expression pattern
23238728 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: Inferred from mutant phenotype
23238728 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

A-kinase anchor protein 12

AKAP-12

gercelin

germ cell lineage protein gercelin

src-suppressed C kinase substrate

testis specific gene A12

v-src suppressed transcript 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00515 AKAP12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Akap12 NCBI NCBI:9590