Mov10l1 - Mov10 like RISC complex RNA helicase 1 Gene

Mus musculus

Also known as Csm; CHAMP

Gene ID: 83456 | Gene type: protein coding

About Mov10l1

Summary

Enables RNA helicase activity and piRNA binding activity. Involved in gamete generation; negative regulation of cell cycle; and piRNA metabolic process. Located in pi-body. Is expressed in heart and testis. Orthologous to human MOV10L1 (Mov10 like RISC complex RNA helicase 1). [provided by Alliance of Genome Resources, Apr 2022]

Mov10l1 Products(1)

mRNA	Protein	Name
NM_031260.2	NP_112550.2	RNA helicase Mov10l1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables RNA helicase activity	IMP IMP: Inferred from mutant phenotype	25762440	MGI
enables piRNA binding	IDA IDA: Inferred from direct assay	25762440	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	20534472	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in male meiosis I	IMP IMP: Inferred from mutant phenotype	20547853	MGI
involved in male meiotic nuclear division	IMP IMP: Inferred from mutant phenotype	20534472	MGI
involved in negative regulation of cell cycle	IDA IDA: Inferred from direct assay	11854500	MGI
involved in piRNA processing	IMP IMP: Inferred from mutant phenotype	20534472	MGI
involved in retrotransposon silencing by piRNA-directed DNA methylation	IMP IMP: Inferred from mutant phenotype	20534472	MGI
involved in spermatogenesis	IMP IMP: Inferred from mutant phenotype	20534472	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in P granule	IDA IDA: Inferred from direct assay	20534472	MGI
located in pi-body	IDA IDA: Inferred from direct assay	23166510	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

RNA helicase Mov10l1

MOV10-like protein 1 homolog	Moloney leukemia virus 10-like 1 protein
cardiac helicase activated by MEF2 protein	cardiac-specific RNA helicase
moloney leukemia virus 10-like protein 1 homolog	putative helicase Mov10l1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08604	MOV10L1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Mov10l1	NCBI	NCBI:54456

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