Mov10l1 - Mov10 like RISC complex RNA helicase 1 Gene

Also Known as Csm; CHAMP

Species: Mus musculus

Gene Type: protein coding
Gene ID: 83456

Summary

Enables RNA helicase activity and piRNA binding activity. Involved in gamete generation; negative regulation of cell cycle; and piRNA metabolic process. Located in pi-body. Is expressed in heart and testis. Orthologous to human MOV10L1 (Mov10 like RISC complex RNA helicase 1). [provided by Alliance of Genome Resources, Apr 2022]

Mov10l1 Products (1)

mRNA Protein Name
NM_031260.2 NP_112550.2 RNA helicase Mov10l1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA helicase activity IMP
IMP: Inferred from mutant phenotype
25762440 MGI
enables piRNA binding IDA
IDA: Inferred from direct assay
25762440 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
20534472 MGI
Biological Process GO Annotation Evidence References Source
involved in male meiosis I IMP
IMP: Inferred from mutant phenotype
20547853 MGI
involved in male meiotic nuclear division IMP
IMP: Inferred from mutant phenotype
20534472 MGI
involved in negative regulation of cell cycle IDA
IDA: Inferred from direct assay
11854500 MGI
involved in piRNA processing IMP
IMP: Inferred from mutant phenotype
20534472 MGI
involved in retrotransposon silencing by piRNA-directed DNA methylation IMP
IMP: Inferred from mutant phenotype
20534472 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
20534472 MGI
Cellular Component GO Annotation Evidence References Source
located in P granule IDA
IDA: Inferred from direct assay
20534472 MGI
located in pi-body IDA
IDA: Inferred from direct assay
23166510 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RNA helicase Mov10l1

  • MOV10-like protein 1 homolog

  • Moloney leukemia virus 10-like 1 protein

  • cardiac helicase activated by MEF2 protein

  • cardiac-specific RNA helicase

  • moloney leukemia virus 10-like protein 1 homolog

  • putative helicase Mov10l1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08604 MOV10L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mov10l1 NCBI NCBI:54456