Dbnl - drebrin-like Gene

Also Known as abp1; Sh3p7

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 83527

Summary

Enables protein C-terminus binding activity. Predicted to be involved in several processes, including Rac protein signal transduction; nervous system development; and podosome assembly. Located in dendrite and postsynaptic density. Orthologous to human DBNL (drebrin like). [provided by Alliance of Genome Resources, Apr 2022]

Dbnl Products (4)

mRNA Protein Name
NM_001277211.1 NP_001264140.1 drebrin-like protein isoform 1
NM_001277212.1 NP_001264141.1 drebrin-like protein isoform 3
NM_001277213.1 NP_001264142.1 drebrin-like protein isoform 4
NM_031352.2 NP_112642.1 drebrin-like protein isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15014124 RGD
enables structural constituent of postsynaptic actin cytoskeleton IDA
IDA: Inferred from direct assay
18829961 RGD
enables structural constituent of postsynaptic actin cytoskeleton IMP
IMP: Inferred from mutant phenotype
18829961 RGD
Biological Process GO Annotation Evidence References Source
involved in postsynaptic actin cytoskeleton organization IDA
IDA: Inferred from direct assay
18829961 RGD
involved in postsynaptic actin cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
18829961 RGD
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
11595038 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
11595038 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
18829961 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
11595038 RGD
is active in presynapse IDA
IDA: Inferred from direct assay
11595038 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

drebrin-like protein

  • SH3 domain-containing protein 7

  • actin-binding protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03551 DBNL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dbnl NCBI NCBI:28988