PDXK - Pdxk pyridoxal kinase Gene

Rattus norvegicus

Gene ID: 83578 | Gene type: protein coding

About PDXK

Summary

Enables pyridoxal binding activity and pyridoxal kinase activity. Involved in several processes, including pyridoxal phosphate biosynthetic process; response to X-ray; and response to progesterone. Predicted to be active in cytosol. Orthologous to human PDXK (pyridoxal kinase). [provided by Alliance of Genome Resources, Apr 2022]

PDXK Products(1)

mRNA	Protein	Name
NM_031769.2	NP_113957.2	pyridoxal kinase

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables organic cyclic compound binding	IPI IPI: Inferred from physical interaction	15975926	RGD
enables pyridoxal binding	IDA IDA: Inferred from direct assay	6255956	RGD
enables pyridoxal kinase activity	IDA IDA: Inferred from direct assay	2988502	RGD
enables small molecule binding	IPI IPI: Inferred from physical interaction	15975926	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of apoptotic process	IMP IMP: Inferred from mutant phenotype	17115225	RGD
involved in pyridoxal phosphate biosynthetic process	IDA IDA: Inferred from direct assay	2988502	RGD
involved in response to X-ray	IEP IEP: Inferred from expression pattern	2928487	RGD
involved in response to amine	IEP IEP: Inferred from expression pattern	17115225	RGD
involved in response to food	IEP IEP: Inferred from expression pattern	10204830	RGD
involved in response to insecticide	IEP IEP: Inferred from expression pattern	2119399	RGD
involved in response to progesterone	IEP IEP: Inferred from expression pattern	3681477	RGD
involved in response to toxic substance	IEP IEP: Inferred from expression pattern	3007703	RGD
involved in response to xenobiotic stimulus	IEP IEP: Inferred from expression pattern	212768	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

pyridoxal kinase

pyridoxal (pyridoxine, vitamin B6) kinase

pyridoxine kinase

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10297	PDXK Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	PDXK	NCBI	NCBI:8566

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