Elovl4 - elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 83603

Summary

Enables fatty acid elongase activity. Involved in fatty acid elongation, polyunsaturated fatty acid. Predicted to be located in endoplasmic reticulum. Predicted to be integral component of endoplasmic reticulum membrane. Is expressed in several structures, including central nervous system; eye; genitourinary system; skin; and spleen. Used to study Stargardt disease. Human ortholog(s) of this gene implicated in corneal dystrophy and spinocerebellar ataxia type 34. Orthologous to human ELOVL4 (ELOVL fatty acid elongase 4). [provided by Alliance of Genome Resources, Apr 2022]

Elovl4 Products (1)

mRNA Protein Name
NM_148941.2 NP_683743.2 elongation of very long chain fatty acids protein 4

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables fatty acid elongase activity EXP
EXP: Inferred from Experiment
18728184 MGI
enables fatty acid elongase activity IMP
IMP: Inferred from mutant phenotype
23479632 MGI
Biological Process GO Annotation Evidence References Source
involved in fatty acid elongation, polyunsaturated fatty acid IMP
IMP: Inferred from mutant phenotype
23479632 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

elongation of very long chain fatty acids protein 4

  • 3-keto acyl-CoA synthase Elovl4

  • ELOVL FA elongase 4

  • ELOVL fatty acid elongase 4

  • very long chain 3-ketoacyl-CoA synthase 4

  • very long chain 3-oxoacyl-CoA synthase 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-117081 C30(ω-hydroxy) Ceramide (d18:1/30:0) 99.46% Unkown
HY-RS04324 ELOVL4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Elovl4 NCBI NCBI:6785