Slc32a1 - solute carrier family 32 member 1 Gene

Also Known as Vgat; Viaat; RUNC-47

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 83612

Summary

Predicted to enable gamma-aminobutyric acid:proton symporter activity and glycine transmembrane transporter activity. Involved in several processes, including gamma-aminobutyric acid transport; hippocampus development; and neurotransmitter loading into synaptic vesicle. Located in inhibitory synapse and synaptic vesicle. Is active in GABA-ergic synapse. Is integral component of synaptic vesicle membrane. Orthologous to human SLC32A1 (solute carrier family 32 member 1). [provided by Alliance of Genome Resources, Apr 2022]

Slc32a1 Products (1)

mRNA Protein Name
NM_031782.2 NP_113970.1 vesicular inhibitory amino acid transporter

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables gamma-aminobutyric acid transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
19843525 RGD
enables gamma-aminobutyric acid:proton antiporter activity IDA
IDA: Inferred from direct assay
9349821 RGD
enables glycine transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
19843525 RGD
Biological Process GO Annotation Evidence References Source
involved in beta-alanine transport IDA
IDA: Inferred from direct assay
23919636 RGD
involved in gamma-aminobutyric acid import IMP
IMP: Inferred from mutant phenotype
19843525 RGD
involved in gamma-aminobutyric acid transport IDA
IDA: Inferred from direct assay
9349821 RGD
involved in gamma-aminobutyric acid transport IMP
IMP: Inferred from mutant phenotype
19843525 RGD
involved in glycine transport IMP
IMP: Inferred from mutant phenotype
19843525 RGD
involved in hippocampus development IEP
IEP: Inferred from expression pattern
18502731 RGD
involved in neurotransmitter loading into synaptic vesicle IDA
IDA: Inferred from direct assay
9349821 RGD
involved in neurotransmitter loading into synaptic vesicle IMP
IMP: Inferred from mutant phenotype
9349821 RGD
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
9822734 RGD
located in inhibitory synapse IDA
IDA: Inferred from direct assay
19914352 RGD
located in presynapse IDA
IDA: Inferred from direct assay
10036231 RGD
located in synapse IDA
IDA: Inferred from direct assay
15681343 RGD
located in synaptic vesicle IDA
IDA: Inferred from direct assay
10036231 RGD
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
9822734 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vesicular inhibitory amino acid transporter

  • GABA and glycine transporter

  • UNC-47 homolog

  • rGVAT

  • solute carrier family 32 (GABA vesicular transporter), member 1

  • vesicular GABA transporter

  • vesicular inhibitory amino acid transporter-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13190 SLC32A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc32a1 NCBI NCBI:140679