Deaf1 - DEAF1 transcription factor Gene

Rattus norvegicus

Also known as NUDR

Gene ID: 83632 | Gene type: protein coding

About Deaf1

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm; fibrillar center; and nucleoplasm. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Vulto-van Silfout-de Vries syndrome. Orthologous to human DEAF1 (DEAF1 transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Deaf1 Products(1)

mRNA	Protein	Name
NM_031801.2	NP_113989.2	deformed epidermal autoregulatory factor 1 homolog

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	9773984	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

deformed epidermal autoregulatory factor 1 homolog

DEAF-1 related transcriptional regulator (NUDR)	nuclear DEAF-1-related transcriptional regulator
suppressin

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-W004705	(2-Aminophenyl)methanol		99.82%	Phase 2

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-E70231	Thrombin-like enzyme		/	Unkown
HY-RS03666	DEAF1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Deaf1	NCBI	NCBI:10522

Name
Email *

	Sorry, but the email address you supplied was invalid.