Deaf1 - DEAF1 transcription factor Gene

Also Known as NUDR

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 83632

Summary

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm; fibrillar center; and nucleoplasm. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Vulto-van Silfout-de Vries syndrome. Orthologous to human DEAF1 (DEAF1 transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Deaf1 Products (1)

mRNA Protein Name
NM_031801.2 NP_113989.2 deformed epidermal autoregulatory factor 1 homolog

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
9773984 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

deformed epidermal autoregulatory factor 1 homolog

  • DEAF-1 related transcriptional regulator (NUDR)

  • nuclear DEAF-1-related transcriptional regulator

  • suppressin

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-W004705 (2-Aminophenyl)methanol 99.82% Phase 2

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-E70231 Thrombin-like enzyme / Unkown
HY-RS03666 DEAF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Deaf1 NCBI NCBI:10522