Sytl2 - synaptotagmin-like 2 Gene

Also Known as Slp2; mKIAA1597

Species: Mus musculus

Gene Type: protein coding
Gene ID: 83671

Summary

Enables neurexin family protein binding activity. Involved in exocytosis and positive regulation of mucus secretion. Acts upstream of or within protein localization to plasma membrane. Located in melanosome and plasma membrane. Is extrinsic component of plasma membrane. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human SYTL2 (synaptotagmin like 2). [provided by Alliance of Genome Resources, Apr 2022]

Sytl2 Products (9)

mRNA Protein Name
NM_001040085.2 NP_001035174.1 synaptotagmin-like protein 2 isoform 2
NM_001040087.2 NP_001035176.1 synaptotagmin-like protein 2 isoform 4
NM_001040088.2 NP_001035177.1 synaptotagmin-like protein 2 isoform 5
NM_001289583.1 NP_001276512.1 synaptotagmin-like protein 2 isoform 6
NM_001289584.1 NP_001276513.1 synaptotagmin-like protein 2 isoform 7
NM_001289585.1 NP_001276514.1 synaptotagmin-like protein 2 isoform 8
NM_001289586.1 NP_001276515.1 synaptotagmin-like protein 2 isoform 4
NM_001368878.1 NP_001355807.1 synaptotagmin-like protein 2 isoform 9
NM_031394.3 NP_113571.2 synaptotagmin-like protein 2 isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables neurexin family protein binding IDA
IDA: Inferred from direct assay
11243866 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12590134 MGI
Biological Process GO Annotation Evidence References Source
involved in exocytosis IDA
IDA: Inferred from direct assay
18266782 MGI
involved in positive regulation of mucus secretion IMP
IMP: Inferred from mutant phenotype
16716193 MGI
acts upstream of or within protein localization to plasma membrane IDA
IDA: Inferred from direct assay
24284068 MGI
Cellular Component GO Annotation Evidence References Source
located in melanosome IDA
IDA: Inferred from direct assay
11773082 MGI
located in membrane IDA
IDA: Inferred from direct assay
11243866 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
11243866 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

synaptotagmin-like protein 2

  • exophilin-4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14123 SYTL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sytl2 NCBI NCBI:54843