HSDL1 - hydroxysteroid dehydrogenase like 1 Gene

Also Known as SDR12C3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 83693

About HSDL1

Cytogenetic location: 16q24.1 Genomic coordinates (GRCh38): 16:84,122,141-84,145,177 (from NCBI)

This gene has 8 transcripts (splice variants), 187 orthologues and 25 paralogues. Ubiquitous expression in thyroid (RPKM 18.3), brain (RPKM 13.0) and 24 other tissues.

Summary

Predicted to enable oxidoreductase activity. Located in intermediate filament Cytoskeleton and mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

HSDL1 Products (2)

mRNA Protein Name
NM_001146051.2 NP_001139523.1 inactive hydroxysteroid dehydrogenase-like protein 1 isoform b
NM_031463.5 NP_113651.4 inactive hydroxysteroid dehydrogenase-like protein 1 isoform a

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19026618 GOA
NOT enables steroid dehydrogenase activity IDA
IDA: Inferred from direct assay
19026618 GOA
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
19026618 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HSDL1 Protein Structure

adh_short

adh_short: short chain dehydrogenase (69 - 236)

  • 0
  • 100
  • 200
  • 300
  • 330 a.a.
Protein Preferred Names Protein Names

inactive hydroxysteroid dehydrogenase-like protein 1

  • short chain dehydrogenase/reductase family 12C member 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06404 HSDL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus HSDL1 RGD RGD:1308433
Macaca mulatta HSDL1 VGNC VGNC:99514
Canis familiaris HSDL1 VGNC VGNC:41812
Felis catus HSDL1 VGNC VGNC:62851
Mus musculus HSDL1 MGD MGI:1919802
Bos taurus HSDL1 VGNC VGNC:29979
Others HSDL1 NCBI