TRPT1 - tRNA phosphotransferase 1 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 83707

About TRPT1

Cytogenetic location: 11q13.1 Genomic coordinates (GRCh38): 11:64,223,799-64,226,257 (from NCBI)

This gene has 16 transcripts (splice variants) and 187 orthologues. Ubiquitous expression in heart (RPKM 18.8), duodenum (RPKM 15.3) and 25 other tissues.

Summary

Predicted to enable tRNA 2'-phosphotransferase activity. Predicted to be involved in tRNA splicing, via endonucleolytic cleavage and ligation. Predicted to act upstream of or within regulation of protein kinase activity. [provided by Alliance of Genome Resources, Apr 2022]

TRPT1 Products (7)

mRNA Protein Name
NM_001033678.4 NP_001028850.2 tRNA 2'-phosphotransferase 1 isoform 1
NM_001160389.2 NP_001153861.1 tRNA 2'-phosphotransferase 1 isoform 3
NM_001160390.2 NP_001153862.1 tRNA 2'-phosphotransferase 1 isoform 1
NM_001160392.2 NP_001153864.1 tRNA 2'-phosphotransferase 1 isoform 4
NM_001160393.1 NP_001153865.1 tRNA 2'-phosphotransferase 1 isoform 5
NM_001330298.2 NP_001317227.1 tRNA 2'-phosphotransferase 1 isoform 6
NM_031472.4 NP_113660.1 tRNA 2'-phosphotransferase 1 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TRPT1 Protein Structure

PTS_2-RNA

PTS_2-RNA: RNA 2'-phosphotransferase, Tpt1 / KptA family (25 - 207)

  • 0
  • 100
  • 200
  • 253 a.a.
Protein Preferred Names Protein Names

tRNA 2'-phosphotransferase 1

  • tRNA splicing 2' phosphotransferase 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15120 TRPT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TRPT1 RGD RGD:1310831
Bos taurus TRPT1 VGNC VGNC:36396
Mus musculus TRPT1 MGD MGI:1333115
Felis catus TRPT1 VGNC VGNC:66594
Macaca mulatta TRPT1 VGNC VGNC:79242
Canis familiaris TRPT1 VGNC VGNC:47881