TTC29 - tetratricopeptide repeat domain 29 Gene

Homo sapiens

Also known as SPGF42; TBPP2A; NYD-SP14

Gene ID: 83894 | Gene type: protein coding

About TTC29

Cytogenetic location: 4q31.22 Genomic coordinates (GRCh38): 4:146,706,617-146,945,864 (from NCBI)

This gene has 8 transcripts (splice variants), 158 orthologues, 6 paralogues and is associated with 2 phenotypes. Restricted expression toward testis (RPKM 35.8).

Summary

Involved in cilium movement and cilium organization. Located in sperm flagellum. Implicated in spermatogenic failure 42. [provided by Alliance of Genome Resources, Apr 2022]

TTC29 Products(3)

mRNA	Protein	Name
NM_001300761.4	NP_001287690.1	tetratricopeptide repeat protein 29 isoform 1
NM_001317806.3	NP_001304735.1	tetratricopeptide repeat protein 29 isoform 3
NM_031956.4	NP_114162.2	tetratricopeptide repeat protein 29 isoform 2

TTC29 Protein Structure

TPR_2

TPR_12

0
100
200
300
400
475 a.a.

Protein Preferred Names

Protein Names

tetratricopeptide repeat protein 29

TPR repeat protein 29

Related Diseases

Diseases

Alias

Spermatogenic Failure 42

SPGF42

Non-Syndromic Male Infertility Due To Sperm Motility Disorder

Non-Syndromic Male Infertility Due Asthenozoospermia

Spermatogenic Failure

Azoospermia	Spgf
Spermatogenic Failure, Susceptibility To	Absent Sperm
Aspermatogenesis	Infertility Due To Azoospermia
Hypospermatogenesis	Azoospermatism

Infertility

Male Infertility Due To Acephalic Spermatozoa

Acephalic Spermatozoa Syndrome

Oligoasthenoteratozoospermia

Oat	Oligoasthenoteratospermia

Primary Ciliary Dyskinesia

Immotile Cilia Syndrome	Kartagener Syndrome
Dextrocardia Bronchiectasis And Sinusitis	Pcd
Ciliary Motility Disorders	Ciliary Motility Disorder
Immotile Ciliary Syndrome	Ciliary Dyskinesia Primary
Ics	Polynesian Bronchiectasis
Dextrocardia-Bronchiectasis-Sinusitis Syndrome	Immotile Cilia Syndrome, Kartagener Type
Primary Ciliary Dyskinesia And Situs Inversus	Primary Ciliary Dyskinesia, Kartagener Type
Siewert Syndrome	Dyskinesia, Ciliary, Primary

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15207	TTC29 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	TTC29	RGD	RGD:1589777
Canis familiaris	TTC29	VGNC	VGNC:47949
Felis catus	TTC29	VGNC	VGNC:66665
Mus musculus	TTC29	MGD	MGI:1920551
Macaca mulatta	TTC29	VGNC	VGNC:82262
Bos taurus	TTC29	VGNC	VGNC:36468

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