TATDN1 - TatD DNase domain containing 1 Gene

Also Known as CDA11

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 83940

About TATDN1

Cytogenetic location: 8q24.13 Genomic coordinates (GRCh38): 8:124,488,494-124,539,088 (from NCBI)

This gene has 21 transcripts (splice variants), 201 orthologues and 2 paralogues. Ubiquitous expression in thyroid (RPKM 16.0), ovary (RPKM 13.3) and 25 other tissues.

Summary

Predicted to enable 3'-5'-exodeoxyribonuclease activity. Predicted to be involved in DNA metabolic process and nucleic acid phosphodiester bond hydrolysis. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TATDN1 Products (5)

mRNA Protein Name
NM_001146160.1 NP_001139632.1 deoxyribonuclease TATDN1 isoform b
NM_001317889.1 NP_001304818.1 deoxyribonuclease TATDN1 isoform c
NM_001317890.1 NP_001304819.1 deoxyribonuclease TATDN1 isoform d
NM_001317891.1 NP_001304820.1 deoxyribonuclease TATDN1 isoform e
NM_032026.4 NP_114415.1 deoxyribonuclease TATDN1 isoform a

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15846844 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TATDN1 Protein Structure

TatD_DNase

TatD_DNase: TatD related DNase (7 - 293)

  • 0
  • 100
  • 200
  • 297 a.a.
Protein Preferred Names Protein Names

deoxyribonuclease TATDN1

  • hepatocarcinoma high expression protein

Related Diseases

Diseases Alias
Lung Cancer

  • Lung Carcinoma

  • Non-Small Cell Lung Carcinoma

  • Lung Cancer, Susceptibility To

  • Lung Cancer, Protection Against

  • Adenocarcinoma Of Lung, Somatic

  • Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer

  • Lung Neoplasm

  • Carcinoma Of Lung

  • Lung Non-Small Cell Carcinoma

  • Non-Small Cell Lung Cancer

  • Nsclc

  • Lung Neoplasms

  • Malignant Neoplasm Of Lung

  • Alveolar Cell Carcinoma

  • Nonsmall Cell Lung Cancer, Somatic

  • Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer, Susceptibility To

  • Lung Cancer, Somatic

  • Lung Cancer, Resistance To

  • Cancer Of Lung

  • Cancer Of Bronchus

  • Cancer Of The Lung

  • Lung Malignancies

  • Lung Malignant Tumors

  • Malignant Lung Tumor

  • Malignant Tumor Of Lung

  • Pulmonary Cancer

  • Pulmonary Carcinoma

  • Pulmonary Neoplasms

  • Respiratory Carcinoma

  • LNCR

  • Adenocarcinoma Of Lung

  • Neoplasm Of Lung

  • Cancer Lung

  • Carcinoma Non-Small Cell Lung

  • Carcinoma, Non-Small-Cell Lung

  • Lung Cancers

  • Lung Carcinomas

  • Cancer, Lung

  • Cancer, Lung, Non-Small Cell

  • Primary Malignant Neoplasm Of Lung

  • Bronchioloalveolar Adenocarcinoma
Non-Invasive Bladder Urothelial Carcinoma

  • Stage 0 Bladder Urothelial Carcinoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14226 TATDN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TATDN1 RGD RGD:1585145
Mus musculus TATDN1 MGD MGI:1916944
Bos taurus TATDN1 VGNC VGNC:35617
Macaca mulatta TATDN1 VGNC VGNC:104498
Canis familiaris TATDN1 VGNC VGNC:47123
Others TATDN1 NCBI