TATDN1 - TatD DNase domain containing 1 Gene

Homo sapiens

Also known as CDA11

Gene ID: 83940 | Gene type: protein coding

About TATDN1

Cytogenetic location: 8q24.13 Genomic coordinates (GRCh38): 8:124,488,494-124,539,088 (from NCBI)

This gene has 21 transcripts (splice variants), 201 orthologues and 2 paralogues. Ubiquitous expression in thyroid (RPKM 16.0), ovary (RPKM 13.3) and 25 other tissues.

Summary

Predicted to enable 3'-5'-exodeoxyribonuclease activity. Predicted to be involved in DNA metabolic process and nucleic acid phosphodiester bond hydrolysis. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TATDN1 Products(5)

mRNA	Protein	Name
NM_001146160.1	NP_001139632.1	deoxyribonuclease TATDN1 isoform b
NM_001317889.1	NP_001304818.1	deoxyribonuclease TATDN1 isoform c
NM_001317890.1	NP_001304819.1	deoxyribonuclease TATDN1 isoform d
NM_001317891.1	NP_001304820.1	deoxyribonuclease TATDN1 isoform e
NM_032026.4	NP_114415.1	deoxyribonuclease TATDN1 isoform a

TATDN1 Protein Structure

TatD_DNase

0
100
200
297 a.a.

Protein Preferred Names

Protein Names

deoxyribonuclease TATDN1

hepatocarcinoma high expression protein

Related Diseases

Diseases

Alias

Lung Cancer

Lung Carcinoma	Non-Small Cell Lung Carcinoma
Lung Cancer, Susceptibility To	Lung Cancer, Protection Against
Adenocarcinoma Of Lung, Somatic	Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In
Nonsmall Cell Lung Cancer	Lung Neoplasm
Carcinoma Of Lung	Lung Non-Small Cell Carcinoma
Non-Small Cell Lung Cancer	Nsclc
Lung Neoplasms	Malignant Neoplasm Of Lung
Alveolar Cell Carcinoma	Nonsmall Cell Lung Cancer, Somatic
Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In	Nonsmall Cell Lung Cancer, Susceptibility To
Lung Cancer, Somatic	Lung Cancer, Resistance To
Cancer Of Lung	Cancer Of Bronchus
Cancer Of The Lung	Lung Malignancies
Lung Malignant Tumors	Malignant Lung Tumor
Malignant Tumor Of Lung	Pulmonary Cancer
Pulmonary Carcinoma	Pulmonary Neoplasms
Respiratory Carcinoma	LNCR
Adenocarcinoma Of Lung	Neoplasm Of Lung
Cancer Lung	Carcinoma Non-Small Cell Lung
Carcinoma, Non-Small-Cell Lung	Lung Cancers
Lung Carcinomas	Cancer, Lung
Cancer, Lung, Non-Small Cell	Primary Malignant Neoplasm Of Lung
Bronchioloalveolar Adenocarcinoma

Non-Invasive Bladder Urothelial Carcinoma

Stage 0 Bladder Urothelial Carcinoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14226	TATDN1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	TATDN1	RGD	RGD:1585145
Mus musculus	TATDN1	MGD	MGI:1916944
Bos taurus	TATDN1	VGNC	VGNC:35617
Macaca mulatta	TATDN1	VGNC	VGNC:104498
Canis familiaris	TATDN1	VGNC	VGNC:47123

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