2. Gene
  3. Cntnap1 - contactin associated protein 1 Gene

Cntnap1 - contactin associated protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Caspr

Gene ID: 84008 | Gene type: protein coding

About Cntnap1

Summary

Enables SH3 domain binding activity. Predicted to be involved in several processes, including myelination; neuronal action potential propagation; and synapse organization. Predicted to act upstream of or within neuron projection development. Located in paranode region of axon. Is integral component of membrane. Is active in presynaptic active zone membrane. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Orthologous to human CNTNAP1 (contactin associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Cntnap1 Products(1)

mRNA Protein Name
NM_032061.2 NP_114450.1 contactin-associated protein 1 precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables SH3 domain binding IDA
IDA: Inferred from direct assay
9118959 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9292722 RGD
Cellular Component GO Annotation Evidence Reference Source
located in axon IDA
IDA: Inferred from direct assay
9292722 RGD
located in paranode region of axon IDA
IDA: Inferred from direct assay
10624965 RGD
is active in presynaptic active zone EXP
EXP: Inferred from Experiment
19187093 RGD
is active in presynaptic active zone IDA
IDA: Inferred from direct assay
19187093 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

contactin-associated protein 1

caspr1

neurexin IV

neurexin-4

p190

paranodin

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02932 CNTNAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cntnap1 NCBI NCBI:8506