Cntnap1 - contactin associated protein 1 Gene

Also Known as Caspr

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 84008

Summary

Enables SH3 domain binding activity. Predicted to be involved in several processes, including myelination; neuronal action potential propagation; and synapse organization. Predicted to act upstream of or within neuron projection development. Located in paranode region of axon. Is integral component of membrane. Is active in presynaptic active zone membrane. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Orthologous to human CNTNAP1 (contactin associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Cntnap1 Products (1)

mRNA Protein Name
NM_032061.2 NP_114450.1 contactin-associated protein 1 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables SH3 domain binding IDA
IDA: Inferred from direct assay
9118959 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9292722 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
9292722 RGD
located in paranode region of axon IDA
IDA: Inferred from direct assay
10624965 RGD
is active in presynaptic active zone EXP
EXP: Inferred from Experiment
19187093 RGD
is active in presynaptic active zone IDA
IDA: Inferred from direct assay
19187093 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

contactin-associated protein 1

  • caspr1

  • neurexin IV

  • neurexin-4

  • p190

  • paranodin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02932 CNTNAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cntnap1 NCBI NCBI:8506