Slc1a6 - solute carrier family 1 member 6 Gene

Also Known as EAAT4

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 84012

Summary

Enables high-affinity glutamate transmembrane transporter activity. Involved in L-glutamate import across plasma membrane. Is integral component of plasma membrane. Part of membrane protein complex. Is active in parallel fiber to Purkinje cell synapse. Is integral component of postsynaptic membrane. Orthologous to human SLC1A6 (solute carrier family 1 member 6). [provided by Alliance of Genome Resources, Apr 2022]

Slc1a6 Products (1)

mRNA Protein Name
NM_032065.2 NP_114454.2 excitatory amino acid transporter 4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables high-affinity L-glutamate transmembrane transporter activity IDA
IDA: Inferred from direct assay
26690923 RGD
enables monoatomic anion transmembrane transporter activity IDA
IDA: Inferred from direct assay
11950769 RGD
Biological Process GO Annotation Evidence References Source
involved in L-glutamate import across plasma membrane IDA
IDA: Inferred from direct assay
26690923 RGD
involved in L-glutamate transmembrane transport IDA
IDA: Inferred from direct assay
26690923 RGD
Cellular Component GO Annotation Evidence References Source
part of membrane protein complex IDA
IDA: Inferred from direct assay
9334410 RGD
is active in parallel fiber to Purkinje cell synapse IDA
IDA: Inferred from direct assay
9570792 RGD
located in plasma membrane IMP
IMP: Inferred from mutant phenotype
26690923 RGD
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
9570792 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

excitatory amino acid transporter 4

  • high affinity aspartate/glutamate transporter

  • high-affinity neuronal glutamate transporter

  • sodium-dependent glutamate/aspartate transporter

  • solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13057 SLC1A6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc1a6 NCBI NCBI:6511