HSDL2 - hydroxysteroid dehydrogenase like 2 Gene

Also Known as C9orf99; SDR13C1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84263

About HSDL2

This gene has 5 transcripts (splice variants), 218 orthologues and 13 paralogues. Ubiquitous expression in fat (RPKM 44.0), liver (RPKM 33.8) and 24 other tissues.

Summary

Predicted to enable oxidoreductase activity. Located in mitochondrion and peroxisome. [provided by Alliance of Genome Resources, Apr 2022]

HSDL2 Products (2)

mRNA Protein Name
NM_001195822.2 NP_001182751.1 hydroxysteroid dehydrogenase-like protein 2 isoform 2
NM_032303.5 NP_115679.2 hydroxysteroid dehydrogenase-like protein 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
NOT enables steroid dehydrogenase activity IDA
IDA: Inferred from direct assay
19703561 GOA
Biological Process GO Annotation Evidence References Source
involved in cholesterol homeostasis IMP
IMP: Inferred from mutant phenotype
38820148 GOA
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
38820148 GOA
located in peroxisome IDA
IDA: Inferred from direct assay
19703561 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HSDL2 Protein Structure

adh_short

adh_short: short chain dehydrogenase (12 - 185)

SCP2

SCP2: SCP-2 sterol transfer family (318 - 411)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 418 a.a.
Protein Preferred Names Protein Names

hydroxysteroid dehydrogenase-like protein 2

  • short chain dehydrogenase/reductase family 13C member 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06405 HSDL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus HSDL2 VGNC VGNC:62852
Bos taurus HSDL2 VGNC VGNC:29980
Canis familiaris HSDL2 VGNC VGNC:41813
Mus musculus HSDL2 MGD MGI:1919729
Macaca mulatta HSDL2 VGNC VGNC:73414
Rattus norvegicus HSDL2 RGD RGD:1305387
Others HSDL2 NCBI