RPAIN - RPA interacting protein Gene

Also Known as RIP; HRIP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84268

About RPAIN

Cytogenetic location: 17p13.2 Genomic coordinates (GRCh38): 17:5,420,182-5,432,877 (from NCBI)

This gene has 17 transcripts (splice variants) and 188 orthologues. Ubiquitous expression in lymph node (RPKM 8.1), testis (RPKM 8.0) and 25 other tissues.

Summary

Predicted to enable metal ion binding activity. Acts upstream of or within several processes, including DNA metabolic process; protein import into nucleus; and response to UV. Located in PML body; cytoplasm; and fibrillar center. [provided by Alliance of Genome Resources, Apr 2022]

RPAIN Products (5)

mRNA Protein Name
NM_001033002.4 NP_001028174.2 RPA-interacting protein isoform b
NM_001160243.2 NP_001153715.1 RPA-interacting protein isoform a
NM_001160244.2 NP_001153716.1 RPA-interacting protein isoform c
NM_001160246.2 NP_001153718.1 RPA-interacting protein isoform d
NM_001160266.2 NP_001153738.1 RPA-interacting protein isoform e

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
acts upstream of or within protein import into nucleus IDA
IDA: Inferred from direct assay
16135809 GOA
acts upstream of or within response to UV IDA
IDA: Inferred from direct assay
16135809 GOA
Cellular Component GO Annotation Evidence References Source
located in PML body IDA
IDA: Inferred from direct assay
16135809 GOA
located in cytoplasm IDA
IDA: Inferred from direct assay
16135809 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RPAIN Protein Structure

RPA_interact_N

RPA_interact_N: Replication protein A interacting N-terminal (7 - 48)

RPA_interact_M

RPA_interact_M: Replication protein A interacting middle (60 - 127)

RPA_interact_C

RPA_interact_C: Replication protein A interacting C-terminal (136 - 218)

  • 0
  • 100
  • 200
  • 219 a.a.
Protein Preferred Names Protein Names

RPA-interacting protein

  • RAP interaction protein

Related Diseases

Diseases Alias
Plantar Fasciitis

  • Fasciitis, Plantar
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12146 RPAIN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus RPAIN RGD RGD:1308492
Canis familiaris RPAIN VGNC VGNC:45705
Macaca mulatta RPAIN VGNC VGNC:76854
Bos taurus RPAIN VGNC VGNC:34097
Mus musculus RPAIN MGD MGI:1916973
Felis catus RPAIN VGNC VGNC:64727
Others RPAIN NCBI