Dhh - desert hedgehog signaling molecule Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 84380

Summary

Predicted to enable calcium ion binding activity; patched binding activity; and zinc ion binding activity. Involved in myelination; response to estradiol; and response to estrogen. Predicted to be located in plasma membrane. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in 46,XY sex reversal and 46,XY sex reversal 7. Orthologous to human DHH (desert Hedgehog signaling molecule). [provided by Alliance of Genome Resources, Apr 2022]

Dhh Products (1)

mRNA Protein Name
NM_053367.1 NP_445819.1 desert hedgehog protein precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in myelination IEP
IEP: Inferred from expression pattern
11746771 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
17109907 RGD
involved in response to estrogen IEP
IEP: Inferred from expression pattern
17109907 RGD
involved in spermatid development IEP
IEP: Inferred from expression pattern
21893610 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

desert hedgehog protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-181525 Mito-DHH chloride / Unkown
HY-RS03733 DHH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17357 Dhh Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23811 Dhh Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dhh NCBI NCBI:50846