Slc17a6 - solute carrier family 17 member 6 Gene

Also Known as Dnpi; Vglut2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 84487

Summary

Enables L-glutamate transmembrane transporter activity. Involved in hippocampus development; neural retina development; and neurotransmitter loading into synaptic vesicle. Located in cytoplasmic vesicle; excitatory synapse; and pericellular basket. Is integral component of synaptic vesicle membrane. Biomarker of transient cerebral ischemia. Orthologous to human SLC17A6 (solute carrier family 17 member 6). [provided by Alliance of Genome Resources, Apr 2022]

Slc17a6 Products (1)

mRNA Protein Name
NM_053427.1 NP_445879.1 vesicular glutamate transporter 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables L-glutamate uniporter activity IDA
IDA: Inferred from direct assay
11502256 RGD
enables chloride channel activity IDA
IDA: Inferred from direct assay
27133463 RGD
enables potassium:proton antiporter activity IDA
IDA: Inferred from direct assay
25433636 RGD
enables sodium:phosphate symporter activity IDA
IDA: Inferred from direct assay
17046815 RGD
Biological Process GO Annotation Evidence References Source
involved in L-glutamate transmembrane transport IDA
IDA: Inferred from direct assay
11502256 RGD
involved in hippocampus development IEP
IEP: Inferred from expression pattern
18502731 RGD
involved in neural retina development IEP
IEP: Inferred from expression pattern
18482716 RGD
involved in neurotransmitter loading into synaptic vesicle IDA
IDA: Inferred from direct assay
11502256 RGD
involved in neurotransmitter loading into synaptic vesicle IMP
IMP: Inferred from mutant phenotype
11502256 RGD
involved in phosphate ion transport IDA
IDA: Inferred from direct assay
29642010 RGD
involved in sodium-dependent phosphate transport IDA
IDA: Inferred from direct assay
17046815 RGD
Cellular Component GO Annotation Evidence References Source
located in early endosome IDA
IDA: Inferred from direct assay
11551935 RGD
located in excitatory synapse IDA
IDA: Inferred from direct assay
16519671 RGD
located in neuron projection IDA
IDA: Inferred from direct assay
11698619 RGD
located in pericellular basket IDA
IDA: Inferred from direct assay
18611437 RGD
located in synaptic vesicle IDA
IDA: Inferred from direct assay
11502256 RGD
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
18502731 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vesicular glutamate transporter 2

  • differentation-associated Na-dependent inorganic phosphate cotransporter

  • differentiation-associated BNPI

  • differentiation-associated Na(+)-dependent inorganic phosphate cotransporter

  • solute carrier family 17 (sodium-dependent inorganic phosphate cotrans

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13039 SLC17A6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc17a6 NCBI NCBI:57084