2. Gene
  3. ACRBP - acrosin binding protein Gene

ACRBP - acrosin binding protein Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CT23; SP32; OY-TES-1

Gene ID: 84519 | Gene type: protein coding

About ACRBP

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:6,638,075-6,647,432 (from NCBI)

This gene has 9 transcripts (splice variants) and 118 orthologues. Restricted expression toward testis (RPKM 162.2).

Summary

The protein encoded by this gene is similar to proacrosin binding protein sp32 precursor found in mouse, guinea pig, and pig. This protein is located in the sperm acrosome and is thought to function as a binding protein to proacrosin for packaging and condensation of the acrosin zymogen in the acrosomal matrix. This protein is a member of the Cancer/testis family of antigens and it is found to be immunogenic. In normal tissues, this mRNA is expressed only in testis, whereas it is detected in a range of different tumor types such as bladder, breast, lung, liver, and colon. [provided by RefSeq, Jul 2008]

ACRBP Products(1)

mRNA Protein Name
NM_032489.3 NP_115878.2 acrosin-binding protein precursor

ACRBP Protein Structure

PBP_sp32

PBP_sp32: Proacrosin binding protein sp32 (1 - 240)

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  • 500
  • 543 a.a.
Protein Preferred Names Protein Names

acrosin-binding protein

acrosin-binding protein, 60 kDa form

Related Diseases

Diseases Alias
Brain Cancer

Adult Brain Tumor

Malignant Neoplasm Of Brain

Brain Neoplasms

Brain Neoplasm

Neoplasm Of Brain

Primary Malignant Neoplasm Of Brain

Brain Tumors

Adult Malignant Brain Neoplasm

Brain Neoplasm, Adult

Bt - Brain Tumour

Malignant Brain Tumour

Malignant Primary Brain Neoplasm

Malignant Primary Brain Tumor

Malignant Tumor Of Adult Brain

Malignant Tumor Of Brain

Primary Brain Neoplasm

Primary Brain Tumor

Tumor Of The Brain

Brain Tumor, Adult

Brain Tumor Primary

Malignant Primary Brain Tumors

Primary Brain Tumors

Cancer, Brain

Brain Tumor, Primary
Cataract 9, Multiple Types

Cataract 9 Multiple Types

CTRCT9

Cataract, Autosomal Dominant

Catc1

Cataract 9, Multiple Types, With Or Without Microcornea

Cataract, Autosomal Recessive Congenital 1

Autosomal Recessive Congenital Cataract 1

Cataract 9 Multiple Types With Or Without Microcornea

Autosomal Dominant Congenital Cataract

Cataract Autosomal Dominant

Cataracts, Autosomal Dominant
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00194 ACRBP Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ACRBP VGNC VGNC:69445
Canis familiaris ACRBP VGNC VGNC:37527
Mus musculus ACRBP MGD MGI:1859515
Bos taurus ACRBP VGNC VGNC:25558
Felis catus ACRBP VGNC VGNC:59530
Rattus norvegicus ACRBP RGD RGD:1564880