MIGA2 - mitoguardin 2 Gene
Also Known as FAM73B; C9orf54
Species: Homo sapiens
About MIGA2
This gene has 14 transcripts (splice variants), 207 orthologues and 1 paralogue. Ubiquitous expression in duodenum (RPKM 12.6), small intestine (RPKM 10.8) and 25 other tissues.
Summary
Enables protein heterodimerization activity and protein homodimerization activity. Involved in mitochondrial fusion. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
MIGA2 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001329990.2 | NP_001316919.1 | mitoguardin 2 isoform 2 |
| NM_032809.4 | NP_116198.3 | mitoguardin 2 isoform 1 |
MIGA2 Protein Structure
Miga: Mitoguardin (31 - 568)
- 0
- 100
- 200
- 300
- 400
- 500
- 593 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
mitoguardin 2 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Pontocerebellar Hypoplasia, Type 10 |
|
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Macaca mulatta | MIGA2 | VGNC | VGNC:74812 |
| Canis familiaris | MIGA2 | VGNC | VGNC:43233 |
| Mus musculus | MIGA2 | MGD | MGI:1922035 |
| Rattus norvegicus | MIGA2 | RGD | RGD:1310887 |
| Felis catus | MIGA2 | VGNC | VGNC:63505 |
| Bos taurus | MIGA2 | VGNC | VGNC:31474 |
| Others | MIGA2 | NCBI |