NFATC2IP - nuclear factor of activated T cells 2 interacting protein Gene

Homo sapiens

Also known as ESC2; NIP45; RAD60

Gene ID: 84901 | Gene type: protein coding

About NFATC2IP

Cytogenetic location: 16p11.2 Genomic coordinates (GRCh38): 16:28,950,937-28,967,092 (from NCBI)

This gene has 7 transcripts (splice variants), 153 orthologues and 3 paralogues. Ubiquitous expression in lymph node (RPKM 11.4), spleen (RPKM 10.6) and 25 other tissues.

Summary

Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

NFATC2IP Products(4)

mRNA	Protein	Name
NM_001394784.1	NP_001381713.1	NFATC2-interacting protein isoform 2
NM_001394785.1	NP_001381714.1	NFATC2-interacting protein isoform 3
NM_001394786.1	NP_001381715.1	NFATC2-interacting protein isoform 4
NM_032815.4	NP_116204.3	NFATC2-interacting protein isoform 1

NFATC2IP Protein Structure

Rad60-SLD

0
100
200
300
419 a.a.

Protein Preferred Names

Protein Names

NFATC2-interacting protein

45 kDa NF-AT-interacting protein

Related Diseases

Diseases

Alias

Tuberculous Empyema

Empyema, Tuberculous

Empyema Tuberculous

Cone-Rod Dystrophy 1

CORD1	Crd1
Cone-Rod Retinal Dystrophy-1	Retinitis Pigmentosa 1

Vitreous Detachment

Posterior Vitreous Detachment

Vitreous Syneresis

Cone-Rod Dystrophy 2

Cone-Rod Dystrophy	CORD2
Cone-Rod Retinal Dystrophy	Rcrd2
Cone-Rod Retinal Dystrophy 2	Crd2
Cord	Crd
Retinal Cone-Rod Dystrophy	Cone-Rod Retinal Dystrophy-2
Retinal Cone-Rod Dystrophy 2	Tapetoretinal Degeneration
Cone-Rod Degeneration	Cone Rod Dystrophy
Dystrophy, Cone-Rod	Dystrophy, Cone-Rod, Type 2
Retinitis Pigmentosa	Retinitis Pigmentosa 2
Progressive Cone-Rod Dystrophy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09240	NFATC2IP Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	NFATC2IP	VGNC	VGNC:63789
Rattus norvegicus	NFATC2IP	RGD	RGD:1359096
Canis familiaris	NFATC2IP	VGNC	VGNC:43768
Bos taurus	NFATC2IP	VGNC	VGNC:32032
Mus musculus	NFATC2IP	MGD	MGI:1329015
Macaca mulatta	NFATC2IP	VGNC	VGNC:75261

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