SYTL1 - synaptotagmin like 1 Gene

Homo sapiens

Also known as JFC1; SLP1

Gene ID: 84958 | Gene type: protein coding

About SYTL1

Cytogenetic location: 1p36.11 Genomic coordinates (GRCh38): 1:27,342,022-27,353,932 (from NCBI)

This gene has 11 transcripts (splice variants), 176 orthologues and 31 paralogues. Broad expression in prostate (RPKM 24.6), skin (RPKM 21.7) and 16 other tissues.

Summary

Predicted to enable neurexin family protein binding activity. Involved in exocytosis. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SYTL1 Products(2)

mRNA	Protein	Name
NM_001193308.2	NP_001180237.1	synaptotagmin-like protein 1 isoform 1
NM_032872.3	NP_116261.1	synaptotagmin-like protein 1 isoform 2

SYTL1 Protein Structure

0
100
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300
400
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562 a.a.

Protein Preferred Names

Protein Names

synaptotagmin-like protein 1

NADPH oxidase-related, C2 domain-containing protein

Related Diseases

Diseases

Alias

Severe Congenital Neutropenia 7

Autosomal Recessive Severe Congenital Neutropenia Due To Csf3r Deficiency

Scn7

Joubert Syndrome 30

JBTS30

Joubert Syndrome, Type 30

Bladder Cancer

Urinary Bladder Cancer	Bladder Carcinoma
Urinary Bladder Carcinoma	Bladder Neoplasm
Bladder Tumor	Cancer, Bladder
Malignant Neoplasm Of Urinary Bladder	Carcinoma Of Bladder
Bladder Cancer, Somatic	Tumor Of The Bladder
Carcinoma Of Urinary Bladder	Bladder Carcinoma Urinary
Cancer Of The Urinary Bladder	Cancer, Urinary Bladder
Malignant Bladder Neoplasm	Malignant Bladder Tumor
Neoplasm Of The Bladder	Neoplasm Of The Urinary Bladder
Tumor Of The Urinary Bladder	Urinary Bladder Neoplasm
BLC	Urothelial Carcinoma Of The Bladder
Bladder Tumors	Urinary Bladder Neoplasms
Bladder Cancer Nos	Vesical Cancer Nos
Malignant Neoplasm Of Bladder, Part Unspecified	Malignant Tumour Of Urinary Bladder
Primary Malignant Neoplasm Of Bladder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14122	SYTL1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SYTL1	VGNC	VGNC:53476
Rattus norvegicus	SYTL1	RGD	RGD:1310715
Macaca mulatta	SYTL1	VGNC	VGNC:78122
Bos taurus	SYTL1	VGNC	VGNC:35546
Mus musculus	SYTL1	MGD	MGI:1933365
Felis catus	SYTL1	VGNC	VGNC:65905

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