Hacl1 - 2-hydroxyacyl-CoA lyase 1 Gene

Also Known as Hpcl2; Phyh2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 85255

Summary

Enables carbon-carbon lyase activity and thiamine pyrophosphate binding activity. Involved in fatty acid alpha-oxidation and methyl-branched fatty acid metabolic process. Located in peroxisome. Orthologous to human HACL1 (2-hydroxyacyl-CoA lyase 1). [provided by Alliance of Genome Resources, Apr 2022]

Hacl1 Products (1)

mRNA Protein Name
NM_053493.1 NP_445945.1 2-hydroxyacyl-CoA lyase 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables carbon-carbon lyase activity IDA
IDA: Inferred from direct assay
10468558 RGD
enables thiamine pyrophosphate binding IDA
IDA: Inferred from direct assay
10468558 RGD
Biological Process GO Annotation Evidence References Source
involved in fatty acid alpha-oxidation IDA
IDA: Inferred from direct assay
10468558 RGD
involved in methyl-branched fatty acid metabolic process IDA
IDA: Inferred from direct assay
10468558 RGD
Cellular Component GO Annotation Evidence References Source
located in peroxisome IDA
IDA: Inferred from direct assay
10468558 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

2-hydroxyacyl-CoA lyase 1

  • 2-HPCL

  • 2-hydroxyphytanoyl-CoA lyase

  • 2-hydroxyphytanoyl-Coenzyme A lyase

  • phytanoyl-CoA 2-hydroxylase 2

  • phytanoyl-Coenzyme A 2-hydroxylase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05988 HACL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22547 Hacl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hacl1 NCBI NCBI:26061