Cnga4 - cyclic nucleotide gated channel subunit alpha 4 Gene

Rattus norvegicus

Also known as Cgn2; rOCNC2

Gene ID: 85258 | Gene type: protein coding

About Cnga4

Summary

Enables cGMP binding activity; intracellular cAMP-activated cation channel activity; and intracellular cGMP-activated cation channel activity. Predicted to be involved in cation transmembrane transport. Predicted to act upstream of or within sensory perception of smell. Located in perikaryon and plasma membrane. Part of intracellular cyclic nucleotide activated cation channel complex. Orthologous to human CNGA4 (cyclic nucleotide gated channel subunit alpha 4). [provided by Alliance of Genome Resources, Apr 2022]

Cnga4 Products(1)

mRNA	Protein	Name
NM_053496.2	NP_445948.2	cyclic nucleotide-gated cation channel alpha-4

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables cGMP binding	IDA IDA: Inferred from direct assay	22786723	RGD
enables intracellularly cAMP-activated cation channel activity	IDA IDA: Inferred from direct assay	10377344	RGD
enables intracellularly cGMP-activated cation channel activity	IDA IDA: Inferred from direct assay	9878057	RGD
enables intracellularly cyclic nucleotide-activated monoatomic cation channel activity	IDA IDA: Inferred from direct assay	7522325	RGD
enables protein-containing complex binding	IDA IDA: Inferred from direct assay	22786723	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in calcium ion transport	IDA IDA: Inferred from direct assay	9878057	RGD
involved in potassium ion transport	IDA IDA: Inferred from direct assay	10377344	RGD
involved in sodium ion transport	IDA IDA: Inferred from direct assay	10377344	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
part of intracellular cyclic nucleotide activated cation channel complex	IDA IDA: Inferred from direct assay	7522482	RGD
located in non-motile cilium membrane	IDA IDA: Inferred from direct assay	10377344	RGD
located in perikaryon	IDA IDA: Inferred from direct assay	12021210	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

cyclic nucleotide-gated cation channel alpha-4

CNCalpha4, CNG5	CNG channel alpha-4
CNG-4	CNG4
cyclic nucleotide gated cation channel	cyclic nucleotide gated channel alpha 4
cyclic nucleotide-gated olfactory channel subunit OCNC2	olfactory cyclic nucleotide-gated channel

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02882	CNGA4 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cnga4	NCBI	NCBI:1262

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