Slc25a27 - solute carrier family 25, member 27 Gene

Also Known as Ucp4

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 85262

Summary

Involved in several processes, including cellular chemical homeostasis; negative regulation of mitochondrial membrane potential; and regulation of glucose import. Located in apical part of cell and neuronal cell body. Colocalizes with mitochondrion. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human SLC25A27 (solute carrier family 25 member 27). [provided by Alliance of Genome Resources, Apr 2022]

Slc25a27 Products (1)

mRNA Protein Name
NM_053500.2 NP_445952.1 mitochondrial uncoupling protein 4

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in inner ear development IEP
IEP: Inferred from expression pattern
21397696 RGD
involved in intracellular triglyceride homeostasis IDA
IDA: Inferred from direct assay
16716360 RGD
involved in negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
16716360 RGD
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
16775390 RGD
involved in negative regulation of mitochondrial calcium ion concentration IMP
IMP: Inferred from mutant phenotype
16775390 RGD
involved in negative regulation of mitochondrial membrane potential IDA
IDA: Inferred from direct assay
21607879 RGD
involved in positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
16716360 RGD
involved in regulation of D-glucose import IDA
IDA: Inferred from direct assay
21607879 RGD
Cellular Component GO Annotation Evidence References Source
located in apical part of cell IDA
IDA: Inferred from direct assay
21397696 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
21397696 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitochondrial uncoupling protein 4

  • uncoupling protein UCP-4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13108 SLC25A27 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc25a27 NCBI NCBI:9481