Prss12 - serine protease 12 Gene

Also Known as Nt

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 85266

Summary

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in exocytosis and zymogen activation. Predicted to act upstream of or within proteolysis. Predicted to be located in axon; cytoplasmic vesicle; and synapse. Predicted to be active in several cellular components, including dendrite; synaptic cleft; and terminal bouton. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability and intellectual disability. Orthologous to human PRSS12 (serine protease 12). [provided by Alliance of Genome Resources, Apr 2022]

Prss12 Products (1)

mRNA Protein Name
NM_053504.1 NP_445956.1 neurotrypsin precursor
Protein Preferred Names Protein Names

neurotrypsin

  • peptidase, serine, 12 (neurotrypsin, motopsin)

  • protease, serine 12

  • protease, serine, 12 neurotrypsin (motopsin)

Orthologs Information

Species Symbol Source ID
Homo sapiens Prss12 NCBI NCBI:8492