2. Gene
  3. Prss12 - serine protease 12 Gene

Prss12 - serine protease 12 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Nt

Gene ID: 85266 | Gene type: protein coding

About Prss12

Summary

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in exocytosis and zymogen activation. Predicted to act upstream of or within proteolysis. Predicted to be located in axon; cytoplasmic vesicle; and synapse. Predicted to be active in several cellular components, including dendrite; synaptic cleft; and terminal bouton. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability and intellectual disability. Orthologous to human PRSS12 (serine protease 12). [provided by Alliance of Genome Resources, Apr 2022]

Prss12 Products(1)

mRNA Protein Name
NM_053504.1 NP_445956.1 neurotrypsin precursor
Protein Preferred Names Protein Names

neurotrypsin

peptidase, serine, 12 (neurotrypsin, motopsin)

protease, serine 12

protease, serine, 12 neurotrypsin (motopsin)

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11246 PRSS12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prss12 NCBI NCBI:8492