2. Gene
  3. CCDC65 - coiled-coil domain containing 65 Gene

CCDC65 - coiled-coil domain containing 65 Gene

  • Gene
  • Protein
  • Agent
Homo sapiens (human)

Also known as DRC2; FAP250; CFAP250; NYD-SP28

Gene ID: 85478 | Gene type: protein coding

About CCDC65

Summary

This gene encodes a sperm tail protein that is highly expressed in adult testis, spermatocytes and spermatids. The protein plays a critical role in the assembly of the nexin-dynein regulatory complex. Mutations in this gene result in primary ciliary dyskinesia. [provided by RefSeq, Nov 2013]

CCDC65 Products(1)

mRNA Protein Name
NM_001286957.2 NP_001273886.1 dynein regulatory complex subunit 2 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
34169321 GOA
Biological Process GO Annotation Evidence Reference Source
involved in cilium assembly IMP
IMP: Inferred from mutant phenotype
24094744 GOA
involved in regulation of cilium movement IMP
IMP: Inferred from mutant phenotype
24094744 GOA
Cellular Component GO Annotation Evidence Reference Source
located in ciliary basal body IDA
IDA: Inferred from direct assay
29257953 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dynein regulatory complex subunit 2

testis development protein NYD-SP28

Related Agents

Pre-clinical Phase
Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P11118A Biotinylated CCDC61 peptide TFA 96.36% Unkown
HY-P11118 Biotinylated CCDC61 peptide / Unkown
HY-RS02034 CCDC15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02041 CCDC25 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02051 CCDC6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02052 CCDC66 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02053 CCDC69 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19249 Ccdc25 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20872 Ccdc6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25738 Ccdc25 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27389 Ccdc6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown