BNI1 - formin BNI1 Gene

Also Known as PPF3; SHE5

Species: Saccharomyces cerevisiae S288C (strain: S288C)

Gene Type: protein coding
Gene ID: 855450

Summary

Enables profilin binding activity. Involved in several processes, including budding cell apical bud growth; Cytoskeleton organization; and regulation of actin Cytoskeleton organization. Located in several cellular components, including actin filament; cellular bud tip; and mating projection tip. Part of incipient cellular bud site and polarisome. Human ortholog(s) of this gene implicated in primary ovarian insufficiency and primary ovarian insufficiency 2A. Orthologous to several human genes including DIAPH2 (diaphanous related formin 2). [provided by Alliance of Genome Resources, Apr 2022]

BNI1 Products (1)

mRNA Protein Name
NM_001183109.2 NP_014128.2 TPA: formin BNI1 [Saccharomyces cerevisiae S288C]

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables profilin binding IDA
IDA: Inferred from direct assay
12134165 SGD
enables profilin binding IMP
IMP: Inferred from mutant phenotype
15923184 SGD
Biological Process GO Annotation Evidence References Source
involved in actin filament bundle assembly IGI
IGI: Inferred from genetic interaction
23671312 SGD
involved in actin filament bundle assembly IMP
IMP: Inferred from mutant phenotype
23671312 SGD
involved in actin nucleation IDA
IDA: Inferred from direct assay
12052901 SGD
involved in barbed-end actin filament capping IDA
IDA: Inferred from direct assay
14561409 SGD
involved in budding cell apical bud growth IGI
IGI: Inferred from genetic interaction
10866679 SGD
involved in budding cell apical bud growth IMP
IMP: Inferred from mutant phenotype
10866679 SGD
involved in cellular hyperosmotic response IGI
IGI: Inferred from genetic interaction
17237521 SGD
involved in cellular hyperosmotic response IMP
IMP: Inferred from mutant phenotype
17237521 SGD
involved in establishment of mitotic spindle orientation IMP
IMP: Inferred from mutant phenotype
10085293 SGD
involved in formin-nucleated actin cable assembly IDA
IDA: Inferred from direct assay
12134165 SGD
involved in formin-nucleated actin cable assembly IGI
IGI: Inferred from genetic interaction
11740491 SGD
involved in formin-nucleated actin cable assembly IMP
IMP: Inferred from mutant phenotype
11740491 SGD
involved in mitotic actomyosin contractile ring assembly IGI
IGI: Inferred from genetic interaction
12419188 SGD
involved in regulation of actin cytoskeleton organization IGI
IGI: Inferred from genetic interaction
17237521 SGD
involved in regulation of actin cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
17237521 SGD
involved in regulation of protein localization IMP
IMP: Inferred from mutant phenotype
10085294 SGD
Cellular Component GO Annotation Evidence References Source
located in actin filament IDA
IDA: Inferred from direct assay
12052901 SGD
located in cell division site IDA
IDA: Inferred from direct assay
26771880 SGD
located in cellular bud neck IDA
IDA: Inferred from direct assay
11154270 SGD
located in cellular bud tip IDA
IDA: Inferred from direct assay
11154270 SGD
is active in cellular bud tip IMP
IMP: Inferred from mutant phenotype
16166638 SGD
is active in cytosol IDA
IDA: Inferred from direct assay
38656798 SGD
located in incipient cellular bud site IDA
IDA: Inferred from direct assay
11154270 SGD
is active in mating projection tip IDA
IDA: Inferred from direct assay
38656798 SGD
located in mating projection tip IDA
IDA: Inferred from direct assay
9082982 SGD
part of polarisome IDA
IDA: Inferred from direct assay
9571251 SGD
part of polarisome IPI
IPI: Inferred from physical interaction
9571251 SGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

formin BNI1