2. Gene
  3. Sh2b1 - SH2B adaptor protein 1 Gene

Sh2b1 - SH2B adaptor protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Sh2b; Sh2-b; Sh2bpsm1

Gene ID: 89817 | Gene type: protein coding

About Sh2b1

Summary

Predicted to enable transmembrane receptor protein tyrosine kinase adaptor activity. Predicted to be involved in intracellular signal transduction; positive regulation of mitotic nuclear division; and regulation of DNA biosynthetic process. Predicted to act upstream of or within lamellipodium assembly and positive regulation of SMAD protein signal transduction. Predicted to be located in cytoplasm and nucleus. Predicted to be active in plasma membrane. Orthologous to human SH2B1 (SH2B adaptor protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Sh2b1 Products(2)

mRNA Protein Name
NM_001048180.1 NP_001041645.1 SH2B adapter protein 1 isoform 2
NM_134456.3 NP_604451.2 SH2B adapter protein 1 isoform 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
9343427 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SH2B adapter protein 1

SH2 domain-containing protein 1B

SH2-B PH domain-containing signaling mediator 1

fceRI gamma-chain-interacting protein SH2-B

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12818 SH2B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sh2b1 NCBI NCBI:25970