2. Gene
  3. ANGEL2 - angel homolog 2 Gene

ANGEL2 - angel homolog 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as Ccr4d; KIAA0759L

Gene ID: 90806 | Gene type: protein coding

About ANGEL2

Cytogenetic location: 1q32.3 Genomic coordinates (GRCh38): 1:212,992,182-213,015,867 (from NCBI)

This gene has 8 transcripts (splice variants), 208 orthologues and 5 paralogues. Ubiquitous expression in brain (RPKM 5.6), lymph node (RPKM 5.1) and 25 other tissues.

Summary

Enables mRNA 3'-UTR binding activity. Involved in 3'-UTR-mediated mRNA stabilization and negative regulation of mitotic cell cycle. Located in Cajal body and cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ANGEL2 Products(5)

mRNA Protein Name
NM_001300753.2 NP_001287682.1 protein angel homolog 2 isoform b
NM_001300755.2 NP_001287684.1 protein angel homolog 2 isoform b
NM_001300757.2 NP_001287686.1 protein angel homolog 2 isoform c
NM_001300758.2 NP_001287687.1 protein angel homolog 2 isoform c
NM_144567.5 NP_653168.2 protein angel homolog 2 isoform a

ANGEL2 Protein Structure

Exo_endo_phos

Exo_endo_phos: Endonuclease/Exonuclease/phosphatase family (170 - 533)

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  • 500
  • 544 a.a.
Protein Preferred Names Protein Names

protein angel homolog 2

Related Diseases

Diseases Alias
Pontocerebellar Hypoplasia, Type 7

Pontocerebellar Hypoplasia Type 7

PCH7

Pontocerebellar Hypoplasia-46,Xy Disorder Of Sex Development Syndrome

Pontocerebellar Hypoplasia 7

Hypoplasia, Pontocerebellar, Type 7
Rheumatoid Arthritis Interstitial Lung Disease

Rheumatoid Lung
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00686 ANGEL2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ANGEL2 VGNC VGNC:37853
Macaca mulatta ANGEL2 VGNC VGNC:69737
Felis catus ANGEL2 VGNC VGNC:59779
Mus musculus ANGEL2 MGD MGI:1196310
Bos taurus ANGEL2 VGNC VGNC:25887
Rattus norvegicus ANGEL2 RGD RGD:1305056