GCNT3 - glucosaminyl (N-acetyl) transferase 3, mucin type Gene

Also Known as GNTM; C24GNT; C2GNT2; C2GNTM; C2/4GnT

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9245

About GCNT3

Cytogenetic location: 15q22.2 Genomic coordinates (GRCh38): 15:59,549,039-59,622,723 (from NCBI)

This gene has 10 transcripts (splice variants), 274 orthologues and 8 paralogues. Biased expression in colon (RPKM 74.9), small intestine (RPKM 64.2) and 7 other tissues.

Summary

This gene encodes a member of the N-acetylglucosaminyltransferase family. The encoded protein is a beta-6-N-acetylglucosamine-transferase that catalyzes the formation of core 2 and core 4 O-glycans on mucin-type glycoproteins.[provided by RefSeq, Apr 2009]

GCNT3 Products (1)

mRNA Protein Name
NM_004751.3 NP_004742.1 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3

GCNT3 Protein Structure

Branch

Branch: Core-2/I-Branching enzyme (133 - 401)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 438 a.a.
Protein Preferred Names Protein Names

beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3

  • C2GnT-mucin type

Related Diseases

Diseases Alias
Colorectal Cancer

  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05341 GCNT3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21579 Gcnt3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28097 Gcnt3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus GCNT3 RGD RGD:631333
Macaca mulatta GCNT3 VGNC VGNC:84342
Felis catus GCNT3 VGNC VGNC:104351
Mus musculus GCNT3 MGD MGI:1919327
Canis familiaris GCNT3 VGNC VGNC:59113
Others GCNT3 NCBI