BCL7C - BAF chromatin remodeling complex subunit BCL7C Gene

Homo sapiens

Also known as SMARCJ3

Gene ID: 9274 | Gene type: protein coding

About BCL7C

Cytogenetic location: 16p11.2 Genomic coordinates (GRCh38): 16:30,833,626-30,894,077 (from NCBI)

This gene has 5 transcripts (splice variants), 112 orthologues and 2 paralogues. Ubiquitous expression in ovary (RPKM 5.5), endometrium (RPKM 4.7) and 25 other tissues.

Summary

This gene is identified by the similarity of its product to the N-terminal region of BCL7A protein. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. The function of this gene has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

BCL7C Products(2)

mRNA	Protein	Name
NM_001286526.2	NP_001273455.1	B-cell CLL/lymphoma 7 protein family member C isoform 1
NM_004765.4	NP_004756.2	B-cell CLL/lymphoma 7 protein family member C isoform 2

BCL7C Protein Structure

BCL_N

0
100
200
217 a.a.

Protein Preferred Names

Protein Names

B-cell CLL/lymphoma 7 protein family member C

B-cell CLL/lymphoma 7C

Related Diseases

Diseases

Alias

Lymphoma

Lymphoid Cancer	Lymphomas
Lymphoid Cancers	Lymphoid Neoplasm
Lymphoma Nos	Nhl - [Non-Hodgkin Lymphoma]
Non-Hodgkin Lymphoma	Non-Hodgkin Lymphoma, Nos
Non-Hodgkin Malignant Lymphoma Nos

Burkitt Lymphoma

Burkitt'S Lymphoma	BL
Burkitt Lymphoma, Somatic	Burkitt Lymphoma/Leukaemia
Burkitt'S Tumor	Burkitt'S Tumor Or Lymphoma
Malignant Lymphoma, Burkitt'S Type	Small Non-Cleaved Cell Lymphoma, Burkitt'S Type
Small Non-Cleaved Cell Lymphoma	Burkitt Tumor
Burkitts Lymphoma	Lymphoma, Small Noncleaved-Cell
Burkitt Tumour	Diffuse Small Noncleaved Malignant Burkitt Lymphoma
Malignant Burkitt Lymphoma	“Burkitt-Like” Lymphoma
Undifferentiated Burkitt Lymphoma	Small Noncleaved Cell Burkitt Lymphoma

Small-Cell Carcinoma Of The Ovary Of Hypercalcemic Type

Hypercalcemic Type Ovarian Small Cell Carcinoma	Small Cell Carcinoma Of The Ovary, Hypercalcemic Type
Ovarian Small Cell Carcinoma, Hypercalcemic Type

Williams-Beuren Syndrome

Williams Syndrome	WBS
Wms	Deletion 7q11.23
Monosomy 7q11.23	Chromosome 7q11.23 Deletion Syndrome, 1.5- To 1.8-Mb
Fanconi Schlesinger Syndrome	Beuren Syndrome
Elfin Facies Syndrome	Elfin Facies With Hypercalcemia
Hypercalcemia-Supravalvar Aortic Stenosis	Ws

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01442	BCL7C Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	BCL7C	MGD	MGI:1332237
Rattus norvegicus	BCL7C	RGD	RGD:1308439
Canis familiaris	BCL7C	VGNC	VGNC:38414
Bos taurus	BCL7C	VGNC	VGNC:58362
Macaca mulatta	BCL7C	VGNC	VGNC:70040
Felis catus	BCL7C	VGNC	VGNC:80552

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