Glce - glucuronyl C5-epimerase Gene

Also Known as Hsepi; 1110017N23Rik; C130034A12Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 93683

Summary

Enables racemase and epimerase activity, acting on carbohydrates and derivatives. Involved in heparan sulfate proteoglycan biosynthetic process and heparin biosynthetic process. Located in Golgi apparatus. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and integumental system. Orthologous to human GLCE (glucuronic acid epimerase). [provided by Alliance of Genome Resources, Apr 2022]

Glce Products (2)

mRNA Protein Name
NM_001368304.1 NP_001355233.1 D-glucuronyl C5-epimerase
NM_033320.5 NP_201577.3 D-glucuronyl C5-epimerase

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables heparosan-N-sulfate-glucuronate 5-epimerase activity IDA
IDA: Inferred from direct assay
11279150 MGI
enables racemase and epimerase activity, acting on carbohydrates and derivatives IDA
IDA: Inferred from direct assay
11274177 MGI
enables racemase and epimerase activity, acting on carbohydrates and derivatives IMP
IMP: Inferred from mutant phenotype
12788935 MGI
Biological Process GO Annotation Evidence References Source
involved in heparan sulfate proteoglycan biosynthetic process IDA
IDA: Inferred from direct assay
11279150 MGI
involved in heparan sulfate proteoglycan biosynthetic process IMP
IMP: Inferred from mutant phenotype
30377379 MGI
involved in heparin biosynthetic process IDA
IDA: Inferred from direct assay
11279150 MGI
Cellular Component GO Annotation Evidence References Source
is active in Golgi apparatus IDA
IDA: Inferred from direct assay
11279150 MGI
located in Golgi apparatus IDA
IDA: Inferred from direct assay
11279150 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

D-glucuronyl C5-epimerase

  • heparan sulfate C5-epimerase

  • heparan sulfate-glucuronic acid C5-epimerase

  • heparin sulfate C5-epimerase

  • heparin/heparan sulfate:glucuronic acid C5-epimerase

  • heparosan-N-sulfate-glucuronate 5-epimerase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05467 GLCE Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Glce NCBI NCBI:26035