1. Gene
  2. Acox2 - acyl-Coenzyme A oxidase 2, branched chain Gene

Acox2 - acyl-Coenzyme A oxidase 2, branched chain Gene

Mus musculus

Also known as THCCox

Gene ID: 93732 | Gene type: protein coding

About Acox2

Summary

Predicted to enable 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity; anion binding activity; and palmitoyl-CoA oxidase activity. Predicted to be involved in several processes, including fatty acid metabolic process; lipid homeostasis; and positive regulation of response to oxidative stress. Predicted to act upstream of or within fatty acid metabolic process. Predicted to be located in cytosol and intracellular membrane-bounded organelle. Predicted to be active in peroxisome. Is expressed in several structures, including heart ventricle; liver; metanephros; and trunk. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 6. Orthologous to human ACOX2 (acyl-CoA oxidase 2). [provided by Alliance of Genome Resources, Apr 2022]

Acox2 Products(2)

mRNA Protein Name
NM_001161667.1 NP_001155139.1 peroxisomal acyl-coenzyme A oxidase 2
NM_053115.2 NP_444345.2 peroxisomal acyl-coenzyme A oxidase 2
Protein Preferred Names Protein Names

peroxisomal acyl-coenzyme A oxidase 2

3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase

3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase

THCA-CoA oxidase

branched chain acyl-CoA oxidase

trihydroxycoprostanoyl-CoA oxidase

Orthologs Information

Species Symbol Source ID
Homo sapiens Acox2 NCBI NCBI:8309