Smarca1 - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 Gene

Also Known as Snf2l; 5730494M04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 93761

Summary

Enables chromatin binding activity. Involved in neuron differentiation. Acts upstream of or within brain development and regulation of neural precursor cell proliferation. Located in chromatin. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Orthologous to human SMARCA1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1). [provided by Alliance of Genome Resources, Apr 2022]

Smarca1 Products (4)

mRNA Protein Name
NM_001290708.2 NP_001277637.1 probable global transcription activator SNF2L1 isoform 2
NM_001358618.1 NP_001345547.1 probable global transcription activator SNF2L1 isoform 3
NM_001358619.1 NP_001345548.1 probable global transcription activator SNF2L1 isoform 1
NM_053123.5 NP_444353.3 probable global transcription activator SNF2L1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
22516202 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within brain development IMP
IMP: Inferred from mutant phenotype
22516202 MGI
involved in neuron differentiation IMP
IMP: Inferred from mutant phenotype
14609955 MGI
acts upstream of or within regulation of neural precursor cell proliferation IGI
IGI: Inferred from genetic interaction
22516202 MGI
acts upstream of or within regulation of neural precursor cell proliferation IMP
IMP: Inferred from mutant phenotype
22516202 MGI
Cellular Component GO Annotation Evidence References Source
located in chromatin IDA
IDA: Inferred from direct assay
22516202 MGI
is active in nucleus IDA
IDA: Inferred from direct assay
22516202 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

probable global transcription activator SNF2L1

  • ATP-dependent helicase SMARCA1

  • DNA-dependent ATPase SNF2L

  • nucleosome-remodeling factor subunit SNF2L

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13403 SMARCA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smarca1 NCBI NCBI:6594