1. Gene
  2. Zfp423 - zinc finger protein 423 Gene

Zfp423 - zinc finger protein 423 Gene

Mus musculus

Also known as Roaz; Ebfaz; nur12; Zfp104; Znf423; ataxia1; mKIAA0760

Gene ID: 94187 | Gene type: protein coding

About Zfp423

Summary

Enables sequence-specific DNA binding activity. Involved in several processes, including Notch signaling pathway; negative regulation of cold-induced thermogenesis; and positive regulation of BMP signaling pathway. Acts upstream of or within several processes, including cerebellar granule cell precursor proliferation; protein localization to cilium; and smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; embryo ectoderm; genitourinary system; and sensory organ. Used to study Dandy-Walker syndrome and cerebellar disease. Human ortholog(s) of this gene implicated in nephronophthisis 14. Orthologous to human ZNF423 (Zinc Finger Protein 423). [provided by Alliance of Genome Resources, Apr 2022]

Zfp423 Products(2)

mRNA Protein Name
NM_001310520.1 NP_001297449.1 zinc finger protein 423 isoform 2
NM_033327.2 NP_201584.2 zinc finger protein 423 isoform 1
Protein Preferred Names Protein Names

zinc finger protein 423

early B-cell factor associated zinc finger protein

early B-cell factor associated zinc finger transcription factor

olf1/EBF-associated zinc finger protein

smad- and Olf-interacting zinc finger protein

zinc finger protein 104