2. Gene
  3. Slc24a3 - solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 Gene

Slc24a3 - solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as NCKX3

Gene ID: 94249 | Gene type: protein coding

About Slc24a3

Summary

Enables calcium, potassium:sodium antiporter activity. Acts upstream of or within bone mineralization; cellular calcium ion homeostasis; and regulation of gene expression. Located in cell periphery. Is expressed in several structures, including alimentary system; central nervous system; dorsal root ganglion; musculature; and neural retina. Orthologous to human SLC24A3 (solute carrier family 24 member 3). [provided by Alliance of Genome Resources, Apr 2022]

Slc24a3 Products(2)

mRNA Protein Name
NM_001356497.1 NP_001343426.1 sodium/potassium/calcium exchanger 3 isoform 1 precursor
NM_053195.3 NP_444425.1 sodium/potassium/calcium exchanger 3 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables calcium, potassium:sodium antiporter activity IDA
IDA: Inferred from direct assay
11294880 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within bone mineralization IMP
IMP: Inferred from mutant phenotype
28602864 MGI
acts upstream of or within intracellular calcium ion homeostasis IMP
IMP: Inferred from mutant phenotype
28602864 MGI
acts upstream of or within negative regulation of gene expression IMP
IMP: Inferred from mutant phenotype
28602864 MGI
acts upstream of or within positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
28602864 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cell periphery IDA
IDA: Inferred from direct assay
19464262 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium/potassium/calcium exchanger 3

Na(+)/K(+)/Ca(2+)-exchange protein 3

solute carrier family 24 member 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13086 SLC24A3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc24a3 NCBI NCBI:57419