CHST10 - carbohydrate sulfotransferase 10 Gene

Also Known as HNK1ST; HNK-1ST

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9486

About CHST10

Cytogenetic location: 2q11.2 Genomic coordinates (GRCh38): 2:100,391,860-100,417,668 (from NCBI)

This gene has 12 transcripts (splice variants), 201 orthologues and 6 paralogues. Broad expression in brain (RPKM 10.4), endometrium (RPKM 4.2) and 21 other tissues.

Summary

This protein encoded by this gene transfers sulfate to the C-3 hydroxyl of terminal glucuronic acid of protein- and lipid-linked oligosaccharides. This protein was first identified as a sulfotransferase that acts on the human natural killer-1 (HNK-1) glycan; HNK-1 is a carbohydrate involved in neurodevelopment and synaptic plasticity.[provided by RefSeq, Feb 2011]

CHST10 Products (1)

mRNA Protein Name
NM_004854.5 NP_004845.1 carbohydrate sulfotransferase 10 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables sulfotransferase activity IDA
IDA: Inferred from direct assay
23269668 GOA
Biological Process GO Annotation Evidence References Source
involved in androgen metabolic process IDA
IDA: Inferred from direct assay
23269668 GOA
involved in estrogen metabolic process IDA
IDA: Inferred from direct assay
23269668 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CHST10 Protein Structure

Sulfotransfer_2

Sulfotransfer_2: Sulfotransferase family (112 - 349)

  • 0
  • 100
  • 200
  • 300
  • 356 a.a.
Protein Preferred Names Protein Names

carbohydrate sulfotransferase 10

  • HNK-1 sulfotransferase

Related Diseases

Diseases Alias
Retinitis Pigmentosa 33

  • RP33

  • Retinitis Pigmentosa, Type 33
Walker-Warburg Syndrome

  • Hard Syndrome

  • Walker-Warburg Congenital Muscular Dystrophy

  • Cerebroocular Dysplasia-Muscular Dystrophy Syndrome

  • Cod-Md Syndrome

  • Chemke Syndrome

  • Hydrocephalus, Agyria And Retinal Dysplasia

  • Cerebroocular Dysgenesis

  • Cerebroocular Dysplasia Muscular Dystrophy Syndrome

  • Hard +/- E Syndrome

  • Pagon Syndrome

  • Warburg Syndrome

  • Hydrocephalus, Agyria, And Retinal Dysplasia

  • Mddga

  • Muscular Dystrophy-Dystroglycanopathy , Type A

  • Muscular Dystrophy-Dystroglycanopathy [With Brain And Eye Anomalies], Type A

  • Hydrocephalus-Agyria-Retinal Dysplasia Syndrome

  • Wws

  • Dystrophy, Muscular, Dystroglycanopathy, Type A
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02682 CHST10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus CHST10 MGD MGI:2138283
Canis familiaris CHST10 VGNC VGNC:39250
Felis catus CHST10 VGNC VGNC:60888
Bos taurus CHST10 VGNC VGNC:27338
Rattus norvegicus CHST10 RGD RGD:621216
Macaca mulatta CHST10 VGNC VGNC:71052
Others CHST10 NCBI