SKIC3 - SKI3 subunit of superkiller complex Gene

Also Known as Ski3; THES; TTC37; KIAA0372

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 9652

Summary

This gene encodes a protein with twenty tetratricopeptide (TPR) repeats. Tetratricopeptide repeat containing motifs are found in a variety of proteins and may mediate protein-protein interactions and chaperone activity. Mutations in this gene are associated with trichohepatoenteric syndrome. [provided by RefSeq, Jul 2010]

SKIC3 Products (1)

mRNA Protein Name
XM_054353898.1 XP_054209873.1 superkiller complex protein 3 isoform X2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16024656 GOA
Biological Process GO Annotation Evidence References Source
involved in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay IDA
IDA: Inferred from direct assay
32006463 GOA
involved in rescue of stalled ribosome IDA
IDA: Inferred from direct assay
32006463 GOA
Cellular Component GO Annotation Evidence References Source
part of Ski complex IDA
IDA: Inferred from direct assay
16024656 GOA
located in cytoplasm IDA
IDA: Inferred from direct assay
16024656 GOA
located in euchromatin IDA
IDA: Inferred from direct assay
16024656 GOA
located in nucleus IDA
IDA: Inferred from direct assay
16024656 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

superkiller complex protein 3

  • SKI complex component SKI3

  • SKI3 homolog

  • SKI3 subunit of superkiller complex protein

  • TPR repeat protein 37

  • tetratricopeptide repeat domain 37

  • thespin

  • tricho-hepatic-enteric syndrome protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-114206 SKI-73 / Unkown