SKIC3 - SKI3 subunit of superkiller complex Gene

Homo sapiens (human)

Also known as Ski3; THES; TTC37; KIAA0372

Gene ID: 9652 | Gene type: protein coding

About SKIC3

Summary

This gene encodes a protein with twenty tetratricopeptide (TPR) repeats. Tetratricopeptide repeat containing motifs are found in a variety of proteins and may mediate protein-protein interactions and chaperone activity. Mutations in this gene are associated with trichohepatoenteric syndrome. [provided by RefSeq, Jul 2010]

SKIC3 Products(1)

mRNA	Protein	Name
XM_054353898.1	XP_054209873.1	superkiller complex protein 3 isoform X2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	16024656	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay	IDA IDA: Inferred from direct assay	32006463	GOA
involved in rescue of stalled ribosome	IDA IDA: Inferred from direct assay	32006463	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
part of Ski complex	IDA IDA: Inferred from direct assay	16024656	GOA
located in cytoplasm	IDA IDA: Inferred from direct assay	16024656	GOA
located in euchromatin	IDA IDA: Inferred from direct assay	16024656	GOA
located in nucleus	IDA IDA: Inferred from direct assay	16024656	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

superkiller complex protein 3

SKI complex component SKI3	SKI3 homolog
SKI3 subunit of superkiller complex protein	TPR repeat protein 37
tetratricopeptide repeat domain 37	thespin
tricho-hepatic-enteric syndrome protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-114206	SKI-73		/	Unkown

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